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Pak J Pharm Sci ; 32(3): 933-936, 2019 May.
Article in English | MEDLINE | ID: mdl-31278702

ABSTRACT

The main objective of this study was to evaluate the hydroethanolic extract of Senna alata for the possible free radical scavenging and cytotoxic properties. Using such hydroethanolic extract, various in vitro antioxidant assays at different concentrations were performed and analyzed. In all the assays, plant extract has good inhibitory effect. Ethanolic extract of Senna alata was further subjected into cytotoxicity against HepG2 cell line. Accordingly, it was also found that the plant extract has appreciable potency against cancer cell lines.


Subject(s)
Antineoplastic Agents, Phytogenic/pharmacology , Free Radical Scavengers/pharmacology , Senna Extract/pharmacology , Senna Plant/chemistry , Antineoplastic Agents, Phytogenic/chemistry , Biphenyl Compounds/chemistry , Ethanol/chemistry , Free Radical Scavengers/chemistry , Hep G2 Cells , Humans , Hydroxyl Radical/metabolism , Nitric Oxide/metabolism , Picrates/chemistry , Plant Leaves/chemistry , Senna Extract/chemistry , Superoxides/metabolism
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