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J Hosp Infect ; 103(4): 461-464, 2019 Dec.
Article in English | MEDLINE | ID: mdl-31513882

ABSTRACT

This study aimed to evaluate the Danish Board of Health's guidance for treating the carriage of meticillin-resistant Staphylococcus aureus (MRSA), focusing on nose-throat carriage and use of supplementary systemic antibiotics. The results of MRSA eradication treatment among 358 patients were analysed, focusing on those with nose (N=58) or throat (N=183) MRSA colonization. The Danish guidance for MRSA treatment was found to be more successful in patients with nose colonization (66%) compared with throat colonization (41%), despite the fact that the cumulative eradication rates were equal after three treatment cycles (71% vs 73%). This study found that supplementation of colonization treatment with systemic antibiotics does not have a positive effect.


Subject(s)
Anti-Bacterial Agents/administration & dosage , Carrier State/drug therapy , Methicillin-Resistant Staphylococcus aureus/isolation & purification , Nasal Mucosa/microbiology , Pharynx/microbiology , Staphylococcal Infections/drug therapy , Administration, Oral , Administration, Topical , Adolescent , Adult , Aged , Aged, 80 and over , Carrier State/microbiology , Child , Child, Preschool , Denmark , Female , Guidelines as Topic , Humans , Male , Middle Aged , Staphylococcal Infections/microbiology , Treatment Outcome , Young Adult
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