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J Clin Microbiol ; 49(6): 2357-60, 2011 Jun.
Article in English | MEDLINE | ID: mdl-21450961

ABSTRACT

We report the first documented case of a posttraumatic fungal keratitis caused by Neosartorya udagawae. The patient was empirically treated with fluconazole until a corneal scraping grew an Aspergillus fumigatus-like fungus, and itraconazole therapy was then established. A sequence-based approach assigned the isolate to the species. Five months after completion of antifungal therapy, endophthalmitis occurred and orbital exenteration was necessary.


Subject(s)
Corneal Diseases/microbiology , Corneal Diseases/pathology , Mycoses/diagnosis , Mycoses/pathology , Neosartorya/isolation & purification , Wounds and Injuries/complications , Adult , Antifungal Agents/administration & dosage , Corneal Diseases/drug therapy , Corneal Diseases/surgery , DNA, Fungal/chemistry , DNA, Fungal/genetics , DNA, Ribosomal/chemistry , DNA, Ribosomal/genetics , DNA, Ribosomal Spacer/chemistry , DNA, Ribosomal Spacer/genetics , Debridement , Fluconazole/administration & dosage , Humans , Itraconazole/administration & dosage , Male , Microbial Sensitivity Tests , Microscopy , Mycoses/drug therapy , Mycoses/surgery , Phylogeny , Sequence Analysis, DNA
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