[Recent outlines in postextractional healing]. / Actualitati privind vindecarea plagii postextractionale.

Postextractional healing was frecquently studied both on animal and human subjects because analysing the mechanisms involved in this process can prevent the occurence of postoperatory complications. Blood cloth formation, maintenance and lysis are the main factors involved in the repair process. A significant purpose of this article is to establish the differences between the two types of healing: per primam and per secundam.

[Effect of antilipemic therapy on patients with diabetes mellitus and obesity]. / Efectele terapiei hipolipemiante asupra unui lot de bolnavi cu diabet zaharat si obezitate.

Fibrates are hypolipemic agents used in noninsulin dependent diabetes mellitus (NIDDM) because these drugs have no influence on glycemia control. The efficiency of fenofibrate (Lipanthyl) was studied in a group of 22 subjects, 30-70 years, obese (body mass index-BMI over 30 kg/m2) or overweight (BMI = 28-30 kg/m2) with hypertension or/and diabetes. All the patients received 200 mg fenofibrate daily, for 6 month, and they had a hypocaloric diet. We measured seric lipids. The results were compared with a control group (20 normal subjects). Under treatment, atherogenic lipids (total cholesterol, LDL-cholesterol and triglycerides) had significantly decreased (p < 0.05) and antiatherogenic fraction (HDL-cholesterol) significantly increased (p < 0.05) compared to initial values. In the mean time, the BMI has significantly decreased under fenofibrate treatment, this body mass loss having a positive influence on lipid metabolism. We observed a better therapeutically response in obese patients vs. the overweight ones, probably due to a higher prevalence of the hypertension in the second subgroup. In conclusion fenofibrate is the drug which can be choose in diabetic dyslipidemia without cardiac disease.

[Determination of urinary iodine as a marker of iodine deficiency]. / Dozarea iodului urinar ca indicator al deficitului iodat.

PURPOSE: Determination of ioduria in order to establish the actual degree of iodine deficiency in school-age children from 4 counties in Moldavia. MATERIALS AND METHODS: Urinary iodine was determined in 927 school-children aged 7-14 years from 4 counties: Suceava, Iasi, Neamt and Botosani. The determination was made by cerium-arsenate method and by a semi-quantitative method. RESULTS: The median value of ioduria was 3 micrograms/dL in Suceava, 8.8 micrograms/dL in Iasi, 7.1 micrograms/dL in Botosani. In Roman-Neamt 93.75% of all samples had a value of ioduria below 10 micrograms/dL. From this point of view, Suceava and Roman are with moderate iodine deficiency; Iasi and Botosani are with mild iodine deficiency. CONCLUSIONS: Despite the existence of a program of iodine prophylaxis, there are still many regions in Moldavia with iodine deficiency, so it is important to have more measures of sanitary education and prophylaxis in these regions.