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Physiol Meas ; 25(1): 159-68, 2004 Feb.
Article in English | MEDLINE | ID: mdl-15005313

ABSTRACT

Magnetic induction tomography of biological tissue is used to reconstruct the changes in the complex conductivity distribution by measuring the perturbation of an alternating primary magnetic field. To facilitate the sensitivity analysis and the solution of the inverse problem a fast calculation of the sensitivity matrix, i.e. the Jacobian matrix, which maps the changes of the conductivity distribution onto the changes of the voltage induced in a receiver coil, is needed. The use of finite differences to determine the entries of the sensitivity matrix does not represent a feasible solution because of the high computational costs of the basic eddy current problem. Therefore, the reciprocity theorem was exploited. The basic eddy current problem was simulated by the finite element method using symmetric tetrahedral edge elements of second order. To test the method various simulations were carried out and discussed.


Subject(s)
Magnetics/instrumentation , Models, Biological , Tomography/methods , Brain Diseases/diagnosis , Electric Impedance , Electromagnetic Fields , Humans , Sensitivity and Specificity
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