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1.
J Pediatr ; 138(4): 596-8, 2001 Apr.
Article in English | MEDLINE | ID: mdl-11295730

ABSTRACT

A significant association with asymptomatic joint hypermobility was observed in 37 children with a history of infantile hypertrophic pyloric stenosis (P =.0016) and their parents (mothers, P <.0001; fathers, P <.05). The subjects with articular hypermobility showed an increased frequency of absent mandibular frenulum, thereby suggesting the presence of a previously unrecognized, systemic abnormality of the extracellular matrix.


Subject(s)
Joint Instability/complications , Pyloric Stenosis/complications , Extracellular Matrix/pathology , Female , Humans , Infant , Joint Instability/diagnosis , Male , Pyloric Stenosis/pathology , Pyloric Stenosis/surgery
2.
J Pediatr ; 136(3): 408-10, 2000 Mar.
Article in English | MEDLINE | ID: mdl-10700703

ABSTRACT

Among 25 patients with hypertrophic pyloric stenosis, a hypoplastic or absent mandibular frenulum was noted in 92%, compared with 1.6% of 319 control infants (P <.001). This previously unrecognized sign may prove helpful in identifying newborns at risk of developing the disorder.


Subject(s)
Labial Frenum/abnormalities , Pyloric Stenosis/complications , Female , Humans , Hypertrophy , Infant, Newborn , Male , Pyloric Stenosis/pathology
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