ABSTRACT
160 patients with stable stress angina pectoris (SSAP) received combined treatment. One of the modalities was information-wave impact generated by devices Azor-IR, Chrono-DMW (microwaves), Chrono-EHF. The impact from Azor-IR proved most effective as it reduced the amount of medication without loss of therapeutic activity.
Subject(s)
Angina Pectoris/therapy , Biofeedback, Psychology/physiology , Ultrasonic Therapy/instrumentation , Aged , Angina Pectoris/diagnosis , Angina Pectoris/rehabilitation , Combined Modality Therapy , Equipment Design , Female , Heart Rate/physiology , Humans , Male , Middle Aged , Severity of Illness IndexABSTRACT
The impact of intravenous infusion of nifedipine and nitroglycerin on invasive central hemodynamic parameters and microcirculation was compared in 94 patients with acute myocardial infarction complicated by heart failure. The artery dilating effects of nifedipine were associated with baseline peripheral vascular tone, so the comparison was made separately in the groups with and without vasoconstriction. Nifedipine seems to be beneficial in the management of heart failure due to acute myocardial infarction in patients with systemic vasoconstriction. In patients with severe pulmonary congestion and normal left ventricular afterload, the intravenous vasodilators are preferable.
Subject(s)
Heart Failure/drug therapy , Hemodynamics/drug effects , Myocardial Infarction/drug therapy , Nifedipine/therapeutic use , Nitroglycerin/therapeutic use , Adult , Aged , Aged, 80 and over , Female , Heart Failure/etiology , Heart Failure/physiopathology , Humans , Infusions, Intravenous , Male , Middle Aged , Myocardial Infarction/complications , Myocardial Infarction/physiopathology , Nifedipine/pharmacology , Nitroglycerin/pharmacologyABSTRACT
The efficacy of intravenous nifedipine was examined in 42 patients with acute myocardial infarction complicated by congestive heart failure. In patients with a higher systemic arteriolar tone, its normalization caused an increase in cardiac output and tissue oxygen supply with a concomitant decrease in pressures in the lesser circulation and the right heart. In contrast, a cardiodepressive effect of the agent was shown in more than a half of the patients with para-normal values of peripheral vascular resistance. The latter is one of the determinants in selecting patients with acute heart failure to be treated with nifedipine.
Subject(s)
Cardiomyopathy, Dilated/drug therapy , Myocardial Infarction/complications , Nifedipine/administration & dosage , Aged , Cardiomyopathy, Dilated/etiology , Cardiomyopathy, Dilated/physiopathology , Drug Administration Schedule , Female , Hemodynamics/drug effects , Hemodynamics/physiology , Humans , Infusion Pumps , Injections, Intravenous , Male , Middle AgedABSTRACT
In 40 patients with massive myocardial infarction, the central hemodynamics was examined by probing the right-sided chambers of the heart and the pulmonary artery. The cardiac output was measured by thermodilution. The gas exchange (respiratory minute volume, capnography, gas analysis of arterial and mixed venous blood) was explored. Arterial hypoxemia was found to be associated with increased intrapulmonary blood shunting in patients with acute myocardial infarction complicated by congestive heart failure. Deterioration of arterial hypoxemia was promoted by a combination of increased overall pulmonary shunting and decreased residual venous oxygenation. Abnormalities in the ventilation-perfusion relations are of great importance.