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J Rheumatol ; 11(5): 624-5, 1984 Oct.
Article in English | MEDLINE | ID: mdl-6512792

ABSTRACT

The prevalence of eosinophilia in 66 patients with rheumatoid arthritis receiving D-penicillamine was determined in a retrospective study. Eosinophilia occurred in 24%. The simultaneous occurrence of toxicity and eosinophilia occurred in 3%. In contrast, eosinophilia only occurred in 10% of those with suspected toxicity. The value of eosinophilia as a marker of toxicity is discussed.


Subject(s)
Arthritis, Rheumatoid/drug therapy , Eosinophilia/chemically induced , Penicillamine/adverse effects , Adult , Aged , Dose-Response Relationship, Drug , Female , Humans , Leukocyte Count , Male , Middle Aged , Penicillamine/therapeutic use , Thrombocytopenia/chemically induced
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