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1.
Clin Colon Rectal Surg ; 34(1): 15-21, 2021 Jan.
Article in English | MEDLINE | ID: mdl-33536845

ABSTRACT

Rectal prolapse frequently occurs in conjunction with functional and anatomic abnormalities of the bowel and pelvic floor. Prolapse surgery should have as its goal not only to correct the prolapse, but also to improve function to the greatest extent possible. Careful history-taking and physical exam continue to be the surgeon's best tools to put rectal prolapse in its functional context. Physiologic testing augments this and informs surgical decision-making. Defecography can identify concomitant middle compartment prolapse and pelvic floor hernias, potentially targeting patients for urogynecologic consultation or combined repair. Other tests, including manometry, ultrasound, and electrophysiologic testing, may be of utility in select cases. Here, we provide an overview of available testing options and their individual utility in rectal prolapse.

2.
J Gastrointest Surg ; 21(2): 398-411, 2017 02.
Article in English | MEDLINE | ID: mdl-27966058

ABSTRACT

Surgery remains a cornerstone of the management of Crohn's disease (CD). Despite the rise of biologic therapy, most CD patients require surgery for penetrating, obstructing, or malignant complications. Optimal surgical therapy requires sophisticated operative judgment and medical optimization. Intraoperatively, surgeons must balance treatment of CD complications against bowel preservation and functional outcome. This demands mastery of multiple techniques for anastomosis and strictureplasty, accurate assessment of bowel integrity for margin minimization, and a comprehensive skillset for navigating adhesions and altered anatomy, controlling thickened mesentery, and safely managing the hostile abdomen. Outside of the operating room, a multi-disciplinary team is critical for pre-operative optimization, patient support, and medical management. Postoperatively, prevention and surveillance of recurrence remain a matter of research and debate, and medical options include older drugs with limited efficacy and tolerability versus biologic agents with greater effect sizes and shorter track records. The evidence base for current management is limited by the inherent challenges of studying a chronic disease marked by heterogeneity and recurrence, but also by a lack of prospective trials incorporating both medical and surgical therapies.


Subject(s)
Crohn Disease/surgery , Intestine, Small , Crohn Disease/complications , Crohn Disease/pathology , Humans , Patient Selection
3.
J Gastrointest Surg ; 18(7): 1358-72, 2014 Jul.
Article in English | MEDLINE | ID: mdl-24820137

ABSTRACT

BACKGROUND: Rectal cancer management has evolved into a complex multimodality approach with survival, local recurrence, and quality of life parameters being the relevant endpoints. Surgical treatment for low rectal cancer has changed dramatically over the past 100 years. DISCUSSION: Abdominoperineal resection, once the standard of care for all rectal cancers, has become much less frequently utilized as surgeons devise and test new techniques for preserving the sphincters, maintaining continuity, and performing oncologically sound ultra-low anterior or local resections. Progress in rectal cancer surgery has been driven by improved understanding of the anatomy and pathophysiology of the disease, innovative surgical technique, improved technology, multimodality approaches, and increased appreciation of the patient's quality of life. The patient with a low rectal cancer, once almost universally destined for impotence and a colostomy, now has the real potential for improved survival, avoidance of a permanent stoma, and preservation of the normal route of defecation.


Subject(s)
Anal Canal/surgery , Colectomy/methods , Neoplasm Recurrence, Local/pathology , Quality of Life , Rectal Neoplasms/surgery , Colectomy/adverse effects , Defecation/physiology , Disease-Free Survival , Evidence-Based Medicine , Female , Humans , Intestinal Mucosa/surgery , Male , Neoplasm Invasiveness/pathology , Neoplasm Recurrence, Local/surgery , Neoplasm Staging , Organ Sparing Treatments , Patient Selection , Recovery of Function , Rectal Neoplasms/mortality , Rectal Neoplasms/pathology , Risk Assessment , Survival Rate , Treatment Outcome , United States
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