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Expert Rev Mol Diagn ; 21(2): 141-160, 2021 02.
Article in English | MEDLINE | ID: mdl-33593219

ABSTRACT

INTRODUCTION: SARS-Cov-2 first appeared in Wuhan, China, in December 2019 and spread all over the world soon after that. Given the infectious nature ofSARS-CoV-2, fast and accurate diagnosis tools are important to detect the virus. In this review, we discuss the different diagnostic tests that are currently being implemented in laboratories and provide a description of various COVID-19 kits. AREAS COVERED: We summarize molecular techniques that target the viral load, serological methods used for SARS-CoV-2 specific antibodies detection as well as newly developed faster assays for the detection of SARS-COV 2 in various biological samples. EXPERT OPINION: In the light of the widespread pandemic, the massive diagnosis of COVID-19, using various detection techniques, appears to be the most effective strategy for monitoring and containing its propagation.


Subject(s)
COVID-19 Nucleic Acid Testing/methods , COVID-19 Nucleic Acid Testing/trends , COVID-19 Serological Testing/methods , COVID-19 Serological Testing/trends , COVID-19/diagnosis , Antibodies, Viral/immunology , Biosensing Techniques , CRISPR-Cas Systems , Clinical Laboratory Techniques , Humans , Immunoassay , Immunoglobulin G/immunology , Immunoglobulin M/immunology , Laboratories , Radiography, Thoracic , Reagent Kits, Diagnostic , Reverse Transcriptase Polymerase Chain Reaction , Tomography, X-Ray Computed
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