Subject(s)
Urinary Calculi/physiopathology , Child , Child, Preschool , Combined Modality Therapy , Cystine/blood , Female , Humans , Hypercalcemia/metabolism , Infant , Kidney Calculi/diagnosis , Kidney Calculi/physiopathology , Male , Uric Acid/blood , Urinary Calculi/diagnosis , Urinary Calculi/therapy , Urinary Tract Infections/physiopathology , Xanthines/bloodABSTRACT
We report a rare case of congenital mumps infection in a newborn girl. Her mother developed bilateral parotitis beginning the day of the delivery. The child was subsequently severely ill and suffered from fever, splenomegaly and thrombocytopenia, however, without parotitis nor pancreatic involvement. Both mother and child recovered well with symptomatic treatment. A review of the literature shows that clinical mumps is rare and usually benign in neonates. However, severe respiratory distress may occur. The recent appearance of mumps outbreaks in adolescents and young adults calls for a reinforcement of mumps vaccination and should prompt an immunological assessment of pregnant women after exposure.
Subject(s)
Mumps/complications , Thrombocytopenia/etiology , Adult , Female , Humans , Infant, Newborn , Mumps/congenital , Mumps/transmission , Pregnancy , Pregnancy Complications, InfectiousSubject(s)
Hospitals, District , Hospitals, Public , Infant, Newborn, Diseases , Humans , Infant, Newborn , SwitzerlandABSTRACT
The prevalence of neonatal urinary tract infection (UTI) was studied in 1,762 high-risk neonates. Symptomatic bacteriuria was found in 1.9% and asymptomatic bacteriuria in 0.5% of these neonates. Male preponderance was 5:1. Clinical manifestations were extremely variable--vomiting, weight loss, and diarrhea being the prominent symptoms. Bacteremia was associated with UTI in six infants. The organisms identified in the urine obtained by suprapubic aspiration were Escherichia coli, Klebsiella, and Proteus. A mixed infection was found in four patients. Roentgenographic examination of the urinary tract showed abnormalities in 44% of the symptomatic patients. It is conclued that symptomatic high-risk newborn infants should be screened for bacteriuria, and that radiological investigations be preformed in those with proven infection.
Subject(s)
Infant, Newborn, Diseases/diagnosis , Urinary Tract Infections/diagnosis , Bacteriuria/diagnosis , Bacteriuria/epidemiology , Bacteriuria/microbiology , Female , Humans , Infant, Newborn , Infant, Newborn, Diseases/epidemiology , Infant, Newborn, Diseases/microbiology , Male , Mass Screening , Risk , Urinary Tract Infections/epidemiology , Urinary Tract Infections/microbiologyABSTRACT
Among 142 high-risk-newborns, 111 could be regularly followed-up to 3 years of age. 79 (71%) are normal, 6 (5.5%) have minor neurological sequels, 9 (8.1%) have major neurological sequels, associated in 4 cases with mental deficiency, 16 (14.5%) have developmental abnormalities (speech delay, behavioral problems, perceptual-motor and praxis disturbances), and one mental deficiency without neurological sequels. Neonatal cerebral distress proved to be the most dangerous clinical situation with regard to the ultimate neurodevelopmental prognosis (73.6% of neurological sequels or developmental abnormalities). The presence of transient abnormalities of tone in the course of the first year of life was associated with ultimate developmental abnormalities in 33.3% of the cases. Social and cultural status seemed to play a role in the intellectual, linguistic and perceptual-motor performance of this group of infants. In spite of these encouraging results, the need for a systematic long term follow-up of high risk newborns is stressed, since neurological sequels and developmental abnormalities are approximately 4 times more frequent in this group than in a normal infantile population.