Regression analysis on forward modeling of diffuse optical tomography system for carcinoma cell detection.

The forward model design was employed in the Diffuse Optical Tomography (DOT) system to determine the optimal photonic flux in soft tissues like the brain and breast. Absorption coefficient (mua), reduced scattering coefficient (mus), and photonic flux (phi) were the parameters subjected to optimization. The Box-Behnken Design (BBD) method of the Response Surface Methodology (RSM) was applied to enhance the Diffuse Optical Tomography experimental system. The DC modulation voltages applied to different laser diodes of 850 nm and 780 nm wavelengths and spacing between the source and detector are the two factors operating on three optimization parameters that predicted the result through two-dimensional tissue image contours. The analysis of the Variance (ANOVA) model developed was substantial (R2 = > 0.954). The experimental results indicate that spacing and wavelength were more influential factors for rebuilding image contour. The position of the tumor in soft tissues is inspired by parameters like absorption coefficient and scattering coefficient, which depend on DC voltages applied to the Laser diode. This regression method predicted the values throughout the studied parameter space and was suitable for enhancement learning of diffuse optical tomography systems. The range of residual error percentage evaluated between experimental and predicted values for mua, mus, and phi was 0.301%, 0.287%, and 0.1%, respectively.

Medical students' perception of the reliability, usefulness and feasibility of unproctored online formative assessment tests.

Medical education has gone online because of the COVID-19 pandemic. Formative assessment is essential to facilitate the learning process in medical education. However, various challenges arise during online assessment, which include reliability, when done without monitoring and practical concerns like Internet connectivity issues. This study was done to assess the medical students' perceptions of the reliability, usefulness, and practical challenges of online tests. One hundred first-year undergraduate medical students taking up online classes and tests in the subject of physiology were enrolled in this study. A questionnaire with items regarding practical challenges, reliability, and usefulness of the online tests, in general, and about different types of online assessment methods, in particular, were sent to the students online. Each item was rated on a five-point Likert scale, and the responses were analyzed anonymously. A large percentage of students used mobile phones (81.4%) to undertake online tests. Although most students (73.2%; P < 0.001) felt that online tests helped them substantially in learning the subject, network connectivity issues were considered to be a matter of serious concern (85.5%, P < 0.001). Among the assessment methods used, viva voce by video conferencing was thought to be most reliable (83%, P < 0.001). Multiple-choice question-based assessment when done online was felt to be more practically feasible with faster feedback than classroom assessment. The results of the study suggest that medical students find online formative assessments helpful for their learning, despite their concerns about reliability and practical challenges.

A rare case of multifocal lymphadenopathy in a young male.

Lymphadenopathy can be caused by localized and systemic diseases. While viral and bacterial infections commonly cause lymphadenitis in young adults, tuberculosis (TB) is a common cause for lymphadenopathy in endemic areas. Besides, lymphadenopathy may be a presenting manifestation of malignancy, systemic disorders and some rare diseases. Thus, relevant evaluation and exclusion of commoner causes is important to clinch the diagnosis. Histopathological examination is mandatory in such patients. We hereby report the case of a young adult male who presented with low-grade fever and abdominal pain with cervical and mesenteric lymphadenopathy in a TB endemic region, but was proved to have atypical presentation of Kikuchi-Fujimoto disease, which is a rare but benign cause of lymphadenopathy.