ABSTRACT
Dilated cardiomyopathy (DCM) is an uncommon complication of Takayasu arteritis (TA) with a prevalence of about 6%. We report a case of 14-year-old girl who presented with dyspnea, bipedal edema, loss of weight, and easy fatigability for three months. She was being treated for DCM for the same duration. Clinical examination revealed absence of both upper limb pulses. Echocardiography revealed features of DCM with severe biventricular dysfunction (ejection fraction 30%). Computed tomography angiogram confirmed the diagnosis of TA and revealed the presence of bilateral renal artery stenosis. Bilateral renal angioplasty was done, and immunosuppressant therapy with oral prednisolone and weekly oral methotrexate was started.
Subject(s)
Cardiomyopathy, Dilated/therapy , Renal Artery Obstruction/surgery , Takayasu Arteritis/complications , Adolescent , Angioplasty , Cardiomyopathy, Dilated/etiology , Female , Humans , Immunosuppressive Agents/administration & dosage , Methotrexate/administration & dosage , Prednisolone/administration & dosage , Renal Artery Obstruction/etiologyABSTRACT
Pompe's disease is a type II glycogen storage disorder resulting from deficiency of α-1,4 glucosidase. It is usually associated with dilated or hypertrophic cardiomyopathy. Association of apical hypertrophic cardiomyopathy is rarely seen. We present a case of a ten-month-old baby with clinical features of both apical hypertrophic cardiomyopathy and Pompe's disease.
