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J Biosci Bioeng ; 118(2): 231-4, 2014 Aug.
Article in English | MEDLINE | ID: mdl-24598302

ABSTRACT

We evaluated bridging of 15 mm nerve gap in rat sciatic nerve injury model with muscle-stuffed vein seeded with olfactory ensheathing cells as a substitute for nerve autograft. Neurophysiological recovery, as assessed by electrophysiological analysis was faster in the constructed biological nerve conduit compared to that of autograft.


Subject(s)
Nerve Regeneration , Sciatic Nerve/physiopathology , Tissue Engineering , Animals , Female , Muscle, Skeletal/pathology , Neural Conduction , Olfactory Nerve/pathology , Peripheral Nerve Injuries/therapy , Rats, Sprague-Dawley , Regenerative Medicine , Sciatic Nerve/pathology , Veins/pathology
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