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Br Med J ; 3(5817): 7-13, 1972 Jul 01.
Article in English | MEDLINE | ID: mdl-5039582

ABSTRACT

Before introducing a more comprehensive screen such as plasma chromatography, with its potential to detect 20 amino-acid disorders-an advantage over screening methods which detect only phenylketonuria-the greatly increased problems of organization and the effect on the community, midwives, paediatric services, and laboratory should be considered. The three years' experience in Birmingham showed a three-fold increase in cases detected and suggests criteria for further investigation and treatment.


Subject(s)
Amino Acid Metabolism, Inborn Errors/diagnosis , Mass Screening , Amino Acid Metabolism, Inborn Errors/blood , Amino Acid Metabolism, Inborn Errors/genetics , Blood Specimen Collection , Chromatography, Paper , Costs and Cost Analysis , Fasting , Food , Histidine/blood , Humans , Hyperlipidemias/diagnosis , Infant, Newborn , Methionine/blood , Midwifery , Phenylalanine/blood , Phenylketonurias/diagnosis , Postal Service , Proline/blood , Time Factors , Tyrosine/blood , United Kingdom
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