1.
Bioorg Med Chem Lett
; 13(12): 1971-5, 2003 Jun 16.
Article
in English
| MEDLINE
| ID: mdl-12781176
ABSTRACT
A number of water soluble bis-amino-2,6-dimethoxyphenyl ester derivatives were found to exhibit improved anaesthetic activity in mice relative to propofol 1. Of the analogues disclosed, 44 was further profiled in rodents and found to be a superior agent to propofol for the induction and maintenance of anaesthesia.