ABSTRACT
Haemorrhagic fever of Creaman virus is a worse virus disease without specific care. It has been described in Africa and in some closed counties to Mali as Mauritania and. The purpose of this study was de determine the serological rate of Crimean Congo Virus Ig G among population living in agro pastoral region in Mali : "Office du Niger" and Baguineda. The study have been taken a period from Jun to November 1991. 228 subject have been involved from "Office du Niger" and 221 sujets from Baguineda area. We used Elisa test to detect the monoclonal antibodies Ig G againt Creaman Congo virus. No antibodies had been founded among the 228 subjects from office du Niger. But 10 subject amont the 212 subject from Baguineda area were positive that means the serological rate of Creaman Congo virus was 4,5% in this area. This study showed that the Creaman Congo virus should circulate in Mali with at lowed spead. The emphazise of the epidemiological survey must be enforced to avoid born and spraying a epidemic due to this virus in Mali and in Africa.
ABSTRACT
From August 1978 to December 1983, 51 insulin-dependent diabetic patients with end-stage renal disease were selected for treatment by continuous ambulatory peritoneal dialysis. There were 27 male and 24 female patients, with a mean age of 52.3 +/- 13.5 years. Forty-five patients dialyzed themselves by continuous ambulatory peritoneal dialysis and six were treated by continuous cyclic peritoneal dialysis. All patients were treated at home. The cumulative duration of treatment was 65.6 patient-years; 14 patients were dialyzed for at least 24 months. Extrarenal complications were frequent at start of continuous ambulatory peritoneal dialysis, including hypertension in 48 patients, proliferative retinopathy in 50, and cardiovascular complications in 30. Age appeared to be the major risk factor, with success rates at 2 years of 78% in patients under age 50 years and only 50% in patients over age 50. The main cause of death was vascular and the main cause of transfer to other therapeutic modalities was abdominal complications or malnutrition or both. Excellent control of blood pressure, uremia, and blood glucose levels was obtained on a daily program of four exchanges. Improvement in visual status was frequently observed, mainly in the young population. In patients with juvenile diabetes, continuous ambulatory peritoneal dialysis should be part of an integrated program with transplantation, while in the elderly, the method offers a unique opportunity for them to treat themselves at home.
Subject(s)
Diabetic Nephropathies/therapy , Kidney Failure, Chronic/therapy , Peritoneal Dialysis, Continuous Ambulatory , Adult , Aged , Cardiovascular Diseases/physiopathology , Diabetes Mellitus, Type 1/physiopathology , Diabetic Nephropathies/physiopathology , Diabetic Retinopathy/physiopathology , Evaluation Studies as Topic , Female , Humans , Hypertension/physiopathology , Male , Middle Aged , Peritoneal Dialysis, Continuous Ambulatory/adverse effects , Visual AcuityABSTRACT
Over the last five years, 46 insulin dependent diabetic patients (mean age 52 +/- 13 years) have been treated by continuous ambulatory peritoneal dialysis (CAPD). Fourteen patients have been on treatment for more than two years. Visual acuity assessed every six months showed that improvement has been observed in 14 eyes (19%), stabilisation in 36 eyes (46%), worsening in 17 eyes (21%), five eyes had a minimal function during the entire follow-up. Systolic blood pressure decreased from 173 +/- 42 mmHg at start of dialysis to 149 +/- 30 and 146 +/- 32 after one and two years. Mean fasting and post-prandial blood glucose assessed monthly in 36 patients treated with four daily intraperitoneal injections of insulin (660 determinations) were respectively 7.5 +/- 3.5 and 8.5 +/- 3.5mmol/L.
