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1.
Microsecond time-resolved X-ray scattering by utilizing MHz repetition rate at second-generation XFELs.
Konold, Patrick E; Monrroy, Leonardo; Bellisario, Alfredo; Filipe, Diogo; Adams, Patrick; Alvarez, Roberto; Bean, Richard; Bielecki, Johan; Bódizs, Szabolcs; Ducrocq, Gabriel; Grubmueller, Helmut; Kirian, Richard A; Kloos, Marco; Koliyadu, Jayanath C P; Koua, Faisal H M; Larkiala, Taru; Letrun, Romain; Lindsten, Fredrik; Maihöfer, Michael; Martin, Andrew V; Mészáros, Petra; Mutisya, Jennifer; Nimmrich, Amke; Okamoto, Kenta; Round, Adam; Sato, Tokushi; Valerio, Joana; Westphal, Daniel; Wollter, August; Yenupuri, Tej Varma; You, Tong; Maia, Filipe; Westenhoff, Sebastian.
Nat Methods ; 2024 Jul 05.
Article in English | MEDLINE | ID: mdl-38969722

ABSTRACT

Detecting microsecond structural perturbations in biomolecules has wide relevance in biology, chemistry and medicine. Here we show how MHz repetition rates at X-ray free-electron lasers can be used to produce microsecond time-series of protein scattering with exceptionally low noise levels of 0.001%. We demonstrate the approach by examining Jɑ helix unfolding of a light-oxygen-voltage photosensory domain. This time-resolved acquisition strategy is easy to implement and widely applicable for direct observation of structural dynamics of many biochemical processes.

2.
Speaking Disparagingly about Minorities and LGBT Patients.
Maihofer, Michael.
J Mich Dent Assoc ; 99(5): 24, 2017 May.
Article in English | MEDLINE | ID: mdl-30230728

Subject(s)
Attitude of Health Personnel , Codes of Ethics , Dental Offices/ethics , Sexual and Gender Minorities , Female , Humans , Male
3.
Specialty Recognition Changes and the ADA Code of Ethics.
Maihofer, Michael.
J Mich Dent Assoc ; 99(1): 22, 83, 2017 01.
Article in English | MEDLINE | ID: mdl-30398312

Subject(s)
American Dental Association , Codes of Ethics , Ethics, Dental , Specialties, Dental/ethics , Humans , United States
4.
Inability to Perform at an Acceptable Level.
Maihofer, Michael.
J Mich Dent Assoc ; 99(3): 26, 69, 2017 03.
Article in English | MEDLINE | ID: mdl-30398793

Subject(s)
Clinical Competence , Codes of Ethics , Ethics, Dental , Retreatment/ethics , Humans
5.
A Big Change - ADA Code Eliminates Specialty Exclusivity.
Maihofer, Michael.
J Mich Dent Assoc ; 99(2): 26, 2017 Feb.
Article in English | MEDLINE | ID: mdl-30398810

Subject(s)
American Dental Association , Codes of Ethics , Ethics, Dental , Specialties, Dental/ethics , Humans , United States
6.
The Problem with an After-Hours Prophy Appointment.
Maihofer, Michael.
J Mich Dent Assoc ; 99(4): 24, 2017 Apr.
Article in English | MEDLINE | ID: mdl-29989716

Subject(s)
After-Hours Care/ethics , Dental Auxiliaries/ethics , Dental Care , Ethics, Dental , Codes of Ethics , Humans
7.
An Unethical Way to Compensate for Lower Insurance Plan Fees.
Maihofer, Michael G.
J Mich Dent Assoc ; 98(4): 24, 2016 Apr.
Article in English | MEDLINE | ID: mdl-27263141

Subject(s)
Ethics, Professional , Fees and Charges , Insurance, Dental/economics , United States
8.
A New Orthodontist Faces a Continuing Care Dilemma.
Maihofer, Michael.
J Mich Dent Assoc ; 98(12): 20, 70, 2016 Dec.
Article in English | MEDLINE | ID: mdl-30721591

Subject(s)
Orthodontists/ethics , Patient Credit and Collection , Practice Management, Dental/ethics , Practice Valuation and Purchase/ethics , Retreatment/economics , Humans , Ownership , Retirement
9.
Ethical Implication of Auxiliary Practice Outside of Scope.
Maihofer, Michael.
J Mich Dent Assoc ; 98(11): 22, 2016 Nov.
Article in English | MEDLINE | ID: mdl-30729767

Subject(s)
Dentist-Patient Relations , Ethics, Dental , Job Description , Personnel Management , Practice Management, Dental/ethics , Humans , Licensure
10.
Pediatric Dentists Treating Special Needs Patients.
Maihofer, Michael G.
J Mich Dent Assoc ; 97(11): 30, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26697660

Subject(s)
Dental Care for Disabled/ethics , Dentists/ethics , Ethics, Dental , Pediatric Dentistry/ethics , Adult , Child , Humans , Michigan , Professional Practice/ethics
11.
Is It Ethical to Advertise Claims of Superiority?
Maihofer, Michael G.
J Mich Dent Assoc ; 97(4): 26, 2015 Apr.
Article in English | MEDLINE | ID: mdl-26268004

Subject(s)
Advertising/ethics , Dentists/ethics , Ethics, Dental , Codes of Ethics , Humans , Michigan , Truth Disclosure/ethics , United States
12.
'Cooking the Books' Redux.
Maihofer, Michael G.
J Mich Dent Assoc ; 97(3): 28, 2015 Mar.
Article in English | MEDLINE | ID: mdl-26281378

Subject(s)
Accounting/ethics , Dentists/ethics , Ethics, Dental , Fees, Dental/ethics , Fraud/ethics , Humans
13.
Refusing Pediatric Referrals.
Maihofer, Michael G.
J Mich Dent Assoc ; 97(7): 24, 66, 2015 Jul.
Article in English | MEDLINE | ID: mdl-26292501

Subject(s)
Dental Care for Children , Dentists , Referral and Consultation , Refusal to Treat , Child , General Practice, Dental , Humans , Interprofessional Relations , Pediatric Dentistry
14.
ADA Launches Fluoride Initiatives.
Maihofer, Michael.
J Mich Dent Assoc ; 97(5): 12, 2015 May.
Article in English | MEDLINE | ID: mdl-26285513

Subject(s)
American Dental Association , Fluoridation , Health Education, Dental , Internet , Blogging , Humans , Social Media , Social Networking , United States
15.
Dr. Maihofer responds.
Maihofer, Michael.
J Mich Dent Assoc ; 97(5): 12, 2015 May.
Article in English | MEDLINE | ID: mdl-26285515

Subject(s)
Accounting/ethics , Dentists/ethics , Ethics, Dental , Humans
16.
The Case of the Kissing Dentist.
Maihofer, Michael G.
J Mich Dent Assoc ; 97(5): 26, 2015 May.
Article in English | MEDLINE | ID: mdl-26285524

Subject(s)
Dentist-Patient Relations/ethics , Dentists/ethics , Ethics, Dental , Humans , Power, Psychological , Sexual Behavior/ethics
17.
Going After Unethical Advertisers.
Maihofer, Michael G.
J Mich Dent Assoc ; 97(6): 20, 2015 Jun.
Article in English | MEDLINE | ID: mdl-26285533

Subject(s)
Advertising/ethics , Dentists/ethics , Ethics, Dental , Codes of Ethics , Humans , Interprofessional Relations , Michigan , Peer Review , United States
18.
Over-treatment of elderly patients.
Maihofer, Michael.
J Mich Dent Assoc ; 96(9): 24, 74, 2014 Sep.
Article in English | MEDLINE | ID: mdl-25318193

Subject(s)
Dental Care for Aged/ethics , Dentists/ethics , Ethics, Dental , Unnecessary Procedures/ethics , Aged , Beneficence , Dentist-Patient Relations/ethics , Humans , Patient Participation , Personal Autonomy , Social Justice , Trust
19.
Ethical considerations when seeing underserved or uninsured patients.
Maihofer, Michael G.
J Mich Dent Assoc ; 96(7): 23, 86, 2014 Jul.
Article in English | MEDLINE | ID: mdl-25163178

Subject(s)
Dental Care/ethics , Dentists/ethics , Ethics, Dental , Medically Uninsured , Vulnerable Populations , Appointments and Schedules , Bioethical Issues , Humans , Social Responsibility , Standard of Care/ethics , United States
20.
Extracting gold from the deceased: it's unethical and illegal.
Maihofer, Michael.
J Mich Dent Assoc ; 96(10): 24, 2014 Oct.
Article in English | MEDLINE | ID: mdl-25647872

Subject(s)
Dentists/legislation & jurisprudence , Ethics, Dental , Funeral Rites , Dentists/ethics , Humans , Michigan
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