ABSTRACT
A 42-year-old male presented to us after an episode of acute anterior human leukocyte antigen (HLA)-B27-associated uveitis, and intraocular pressure (IOP) in the right eye was 4 mmHg. Ultrasound biomicroscopy revealed ciliary body edema with supraciliary effusion. He was on a frequent topical corticosteroid, and oral steroid in addition to receiving a periocular injection depot corticosteroid 20 days back. He was started on treatment with subcutaneous golimumab (GLM). After a month, his IOP in the right eye was 14 mm of Hg with UBM showing resolution of ciliary body edema. GLM can be useful in the management of steroid-resistant cases of HLA B-27-associated ocular hypotony.
Subject(s)
Antibodies, Monoclonal/administration & dosage , Ciliary Body/diagnostic imaging , HLA-B27 Antigen/immunology , Intraocular Pressure/physiology , Ocular Hypotension/immunology , Adult , Humans , Injections, Subcutaneous , Male , Microscopy, Acoustic , Ocular Hypotension/drug therapy , Ocular Hypotension/physiopathology , Tonometry, OcularABSTRACT
PURPOSE: To report a case of retinal vasculitis in a patient with ankylosing spondylitis. BACKGROUND: Posterior segment involvement in HLA B-27-associated uveitis is uncommon but we report a case wherein retinal vasculitis was associated with HLA-B 27 uveitis. CASE: A 36-year-old male, a diagnosed case of ankylosing spondylitis, presented to us with severe anterior segment inflammation associated vitritis in both the eyes. He received topical, oral steroid and immunosuppressive and 3½-month after the control of his uveitis, he underwent cataract surgery in his left eye. Fundus evaluation following cataract surgery revealed sclerosed retinal vessels and wide-field fundus fluorescein angiography confirmed retinal vascular involvement in both the eyes. CONCLUSION: Retinal vasculitis, though rare can occur in patients with ankylosing spondylitis especially in conditions which present with panuveitis-like picture.
