ABSTRACT
Metastatic carcinoma of the spleen occurs in a setting of widespread malignant disease. Solitary parenchymal splenic metastasis of ovarian carcinoma is rare. We report a case of a 59-year-old woman who presented with an elevated serum CA125 level due to a solitary splenic metastasis after a long disease-free period. She was treated with laparoscopic splenectomy followed by chemotherapy. The literature contains 16 cases of solitary parenchymal splenic metastasis of ovarian carcinoma. Our case is the third case that was treated with laparoscopic splenectomy. We review the literature, and we focus on the laparoscopic approach in managing these cases.
Subject(s)
Cystadenocarcinoma, Serous/secondary , Ovarian Neoplasms/pathology , Splenic Neoplasms/secondary , CA-125 Antigen/blood , Cystadenocarcinoma, Serous/surgery , Female , Humans , Laparoscopy/methods , Middle Aged , Ovarian Neoplasms/therapy , Spleen/pathology , Spleen/surgery , Splenic Neoplasms/surgeryABSTRACT
Pure primary squamous cell carcinoma (SCC) of the breast is a rare condition. The exact histogenesis of this malignancy is unclear. The rarity of the condition makes it difficult to draw firm conclusions on the course of the disease and the overall prognosis. We report a case of pure primary SCC of the breast occurring in a 62-year-old woman and presenting as an enlarged breast lesion with bleeding. We also review the literature for all cases of pure primary SCC.