Subject(s)
AIDS-Related Opportunistic Infections/diagnosis , Cryptosporidiosis/diagnosis , HIV-1 , Tuberculosis, Miliary/diagnosis , AIDS-Related Opportunistic Infections/ethnology , AIDS-Related Opportunistic Infections/pathology , Acute Disease , Adult , Cryptosporidiosis/pathology , Humans , Male , Moscow , Tuberculosis, Miliary/ethnology , Tuberculosis, Miliary/pathology , Zambia/ethnologyABSTRACT
The first AIDS patient was a homosexual male who contacted HIV infection in 1982 in Tanzania. In December 1985 the first sign of Kaposi's sarcoma was noted in this patient. HIV infection was diagnosed in him only in February 1987. He was treated with AZT, reaferon, immunoglobulin and underwent electronic therapy. His state of health was stable till February 1991. Then he got severe bacterial pneumonia, candidosis. Pancytopenia progressed. The dose of AZT (0.8 g daily) was increased and intensive antibiotic therapy and the course of diflucan were prescribed. In spite of this treatment the number of CD4 lymphocytes catastrophically decreased (CD4 = 0.01 x 10(9)/l) and the patient died. Thus, more than 63 months passed from the date of the appearance of the first symptoms of AIDS in the patient to his death.
Subject(s)
HIV Infections/diagnosis , HIV-1 , AIDS-Related Opportunistic Infections/diagnosis , AIDS-Related Opportunistic Infections/therapy , Acquired Immunodeficiency Syndrome/diagnosis , Acquired Immunodeficiency Syndrome/therapy , Adult , Candidiasis, Oral/diagnosis , Candidiasis, Oral/therapy , Combined Modality Therapy , HIV Infections/therapy , Hospitalization , Humans , Leukoplakia, Oral/diagnosis , Leukoplakia, Oral/therapy , Male , Pulmonary Fibrosis/diagnosis , Pulmonary Fibrosis/therapy , Sarcoma, Kaposi/diagnosis , Sarcoma, Kaposi/therapy , Skin Neoplasms/diagnosis , Skin Neoplasms/therapy , Tanzania , Tongue Neoplasms/diagnosis , Tongue Neoplasms/therapy , USSRABSTRACT
To determine the prevalence of Pneumocystis carinii in the HIV-infection department, a simultaneous survey was made of 33 HIV-infected patients at various stages of the disease, of close relatives that were nursing the patients in the unit (n-7), and of medical staff of the department (n-20). Patients with toxic infections who were on another floor of the same hospital and medical students were examined as a control group. For detection of P. carinii antigen, smears from the deep airways were tested in the immunofluorescence. P. carinii was detected in 87.7% of HIV-infected patients, in 71.4% of their relatives and in 80.0% of the medical staff, in 16.6% of control patients and 27.7% of students. The main type of the infectious process in pneumocystosis is its carriage; 2 patients at a stage of relapses (IIIB) that corresponds to AIDS were recorded as having pneumocystis pneumonia.
