The Effect of Melasma on the Quality of Life in People with Darker Skin Types Living in Durban, South Africa.

Melasma is a common skin disorder of acquired hyperpigmentation that appears commonly on the face. Although asymptomatic, melasma causes psychosocial and emotional distress. This study aimed to assess melasma's severity on people with darker skin types, evaluate the effects of melasma on the quality of life (QoL), and establish QoL predictors in affected individuals. This was a cross-sectional analytic study that enrolled 150 patients from three private dermatology clinics in Durban, South Africa who were diagnosed with melasma. The severity of melasma alongside QoL were measured using a melasma area and severity index (MASI) score and melasma quality of life scale (MELASQoL), respectively. The associations among factors and QoL were explored using multivariable methods and stepwise regression analysis. p-values less than 0.05 were considered significant. Enrolled patients were predominantly females (95%), of which 76% were of black African ethnicity, 9% were of Indian ethnicity, and 15% had mixed ancestry, with an average age of 47.30 years. Family history revealed that 61% had no prior melasma cases, while 39% had affected relatives, most commonly mothers (41%). The cheeks were the most common site for melasma. MASI score of Masi (ß = 0.209, t = 2.628, p < 0.001), the involvement of cheeks (ß = -0.268, t = -3.405, p < 0.001), level of education (ß = -0.159, t = -2.029, p = 0.044), and being menopausal (ß = -0.161, t = -2.027, p = 0.045) were found to be predictors of QoL. A regression model was created to forecast MELASQoL using these four predictors. This equation's significance lies in its ability to enable the remote assessment of MELASQoL based on these four variables. It offers a valuable tool for researchers and medical professionals to quantitatively and objectively evaluate the impact of melasma on an individual's quality of life.

Mental Health Challenges during COVID-19 Pandemic: Experiences of Primary Healthcare Nurses in Durban, South Africa.

The COVID-19 pandemic had a significant impact on the mental health of individuals globally, and primary healthcare (PHC) nurses play a critical role in providing mental healthcare services. However, limited research has explored the experiences of PHC nurses in providing mental healthcare services during the COVID-19 pandemic. This study explored the experiences of PHC nurses in providing mental healthcare services during the pandemic in Durban, South Africa. The aim was to identify the challenges faced by healthcare providers and the potential for innovative approaches to improve access to care. A qualitative, exploratory design guided the study, and data were collected through in-depth interviews with twelve PHC nurses purposively selected. Thematic analysis was used to analyze the data. Findings from interviews with PHC nurses reveal that the pandemic exacerbated existing challenges, including medication adherence issues, fear and uncertainty among patients, vaccine hesitancy, decreased clinic visits, and the mental and emotional toll on both patients and healthcare workers. PHC nurses adapted their services by increasing outreach efforts, prioritizing patient care, and utilizing technology and non-governmental organizations' (NGOs) support. Challenges included reduced patient visits, complexities in healthcare provision, and a lack of adequate support. Positive changes observed include increased mental health awareness among healthcare professionals and younger generations. Recommendations include implementing outreach and awareness campaigns, providing accurate information about COVID-19 and vaccinations, and promoting cultural sensitivity in mental healthcare provision.

Evaluation of the Occluding Characteristics of Nanosized Eggshell/Titanium Dioxide with or without Saliva.

OBJECTIVES: The study reports on the effectiveness of a ball-milled nanosized titanium dioxide composite (EB@TiO2) for DH management in comparison with commercial desensitizing paste with and without saliva. MATERIALS AND METHODS: Forty-nine dentine specimens were prepared from extracted bovine anterior teeth. Twenty-one of the specimens were brushed with three desensitizing toothpaste for 7 days, namely: Group 1; EB@TiO2, Group 2; Colgate Pro-relief; and Group 3; Sensodyne repair (n = 7). Twenty-four specimens were brushed with the toothpaste for 7 days and stored in artificial saliva (control) after brushing. Each specimen was subsequently posttreated in citric acid solution to test its stability in acidic condition. Field scanning electron microscope was used to evaluate the effectiveness of the dentine tubules occlusion. The biocompatibility of the composite was tested using BHK21 cell line. STATISTICAL ANALYSIS: One-way analysis of variance was used to analyze the percentage occluded area ratio values for all specimens (α = 0.05). Independent t-test was further used to evaluate the occlusion differences with saliva and without saliva. RESULTS AND CONCLUSIONS: The number of dentine tubules decreased significantly after 7 days of brushing. Overall, the occlusion observe for EB@TiO2 were significantly better than for Colgate Pro-relief and Sensodyne repair (p < 0.05). BHK21 assay suggested that composite had no significant effect on the BHK21 cell line. This study demonstrated that the composite effectively occluded open dentine tubules within 7 days of brushing.