Subject(s)
Blood Platelets/physiology , Hematologic Diseases/blood , Acute Disease , Adolescent , Adult , Anemia, Aplastic/blood , Anemia, Aplastic/diagnostic imaging , Anemia, Aplastic/therapy , Blood Platelets/diagnostic imaging , Blood Transfusion , Cell Survival , Chromium Radioisotopes , Chronic Disease , Female , Hematologic Diseases/diagnostic imaging , Hematologic Diseases/therapy , Humans , Leukemia/blood , Leukemia/diagnostic imaging , Leukemia/therapy , Male , Platelet Transfusion , Polycythemia Vera/blood , Polycythemia Vera/diagnostic imaging , Polycythemia Vera/therapy , Radionuclide Imaging , Time FactorsABSTRACT
Radiologic investigation of concealed gastro-intestinal hemorrhage with 51Cr was conducted for its detection and quantitative estimation in 102 patients with iron-deficiency anemia (IDA), loss of blood from the digestive tract was detected in 52 of them. A definite relationship was noted between the volume of hemorrhage and the disease responsible for the development of IDA. Moderate hemorrhage from 2.5 to 15.0 ml/day was detected in chronic inflammatory diseases of the gastro-intestinal tract (GIT): chronic gastritis, colitis. High volumes of hemorrhage are characteristic of diseases attended by gross changes in the digestive tract: polyps, tumors, diverticula, varicosis in GIT. It has been shown that the radiologic method of quantitative estimation of concealed gastro-intestinal hemorrhage with the use of 51Cr is highly sensitive and accurate, that permitted the authors to recommend this method for both practical and scientific investigations.