ABSTRACT
Five novel HLA-C alleles detected by next-generation sequencing: HLA-C*02:02:73, -C*03:04:106, -C*06:382, -C*07:1114Q and -C*12:408.
Subject(s)
Alleles , HLA-C Antigens , High-Throughput Nucleotide Sequencing , Histocompatibility Testing , Humans , High-Throughput Nucleotide Sequencing/methods , HLA-C Antigens/genetics , Histocompatibility Testing/methods , Exons , Sequence Analysis, DNA/methodsABSTRACT
Identification of the novel HLA-A*02:1148 and HLA-B*44:386 alleles by next-generation sequencing.
Subject(s)
HLA-A Antigens , High-Throughput Nucleotide Sequencing , Humans , Alleles , HLA-B Antigens/geneticsABSTRACT
HLA-B*35:592 differs from HLA-B*35:03:01:01 by one nucleotide substitution in exon 4.
Subject(s)
Genes, MHC Class I , Nucleotides , Humans , Alleles , Base Sequence , Russia , Sequence Analysis, DNAABSTRACT
Three novel alleles were identified during routine next generation sequencing.
Subject(s)
HLA-A Antigens , HLA-B Antigens , HLA-DRB1 Chains , Alleles , HLA-DRB1 Chains/genetics , High-Throughput Nucleotide Sequencing , HumansABSTRACT
NGS typing reveals six novel alleles among 192 class I and class II alleles.
Subject(s)
Alleles , Gene Frequency , Haplotypes , Humans , RussiaABSTRACT
HLA-C*07:944 differs from HLA-C*07:01:01:01 by one nucleotide substitution in codon 325 in exon 6.
Subject(s)
Genes, MHC Class I , HLA-C Antigens , Alleles , Exons/genetics , HLA-C Antigens/genetics , High-Throughput Nucleotide Sequencing , HumansABSTRACT
One nucleotide replacement in codon 144 of HLA-B*13:45 results in a novel allele, HLA-B*13:153.
Subject(s)
Genes, MHC Class I , HLA-B Antigens , Alleles , Codon , HLA-B Antigens/genetics , Humans , Russia , Sequence Analysis, DNAABSTRACT
Two novel HLA alleles were detected using next-generation sequencing.
Subject(s)
Genes, MHC Class I , HLA-C Antigens , Alleles , HLA-A Antigens/genetics , HLA-C Antigens/genetics , High-Throughput Nucleotide Sequencing , Humans , RussiaABSTRACT
The new HLA-B*15:583 and DRB1*11:279 alleles identified in Buryat and Russian individuals, respectively.
Subject(s)
HLA-A Antigens , HLA-B Antigens , Alleles , Gene Frequency , HLA-B Antigens/genetics , HLA-DRB1 Chains/genetics , Haplotypes , Humans , RussiaABSTRACT
Two novel alleles, HLA-A*02:942 and HLA-DQB1*06:02:47, are characterized.
Subject(s)
HLA-A Antigens , Alleles , HLA-A Antigens/genetics , HLA-DQ beta-Chains/genetics , HumansABSTRACT
NGS typing reveals 2 novel alleles amongst 206 class I and class II alleles.
