Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size.

The relationship between body size and metabolism of goats remains poorly studied. The study evaluated the neonatal metabolic adjustments and elucidated the relationship between serum metabolites and body size in 39 single-born dwarf and normal-sized goat kids. Body weight, length and height of kids were recorded at birth and blood samples were collected from the dwarf and normal-sized (Red Sokoto and Sahel) goats on Days 0 (birth), 3, 10 and 20, postnatal. Also, the body mass index (BMI) was calculated and the concentration of metabolic markers was determined. Results revealed that values of BMI, body weight, length and height were lowest (P < 0.01) in the dwarf, followed by values in Red Sokoto kids, while the Sahel kids had the highest (P < 0.01) values. Conversely, the concentration of triglyceride at birth was highest (P < 0.05) in the dwarf, moderate in Red Sokoto and lowest in Sahel goats. Similarly, the Sahel goat kids had the lowest neonatal (P < 0.05) concentration of serum cholesterol. Neonatal concentrations of serum albumin and urea were higher in Sahel than Red Sokoto (P < 0.05) and the dwarf (P > 0.05) goats. Concentration of serum albumin was lower (P < 0.05) at birth, but significantly increased later, while values of serum urea concentration were higher (P < 0.05) at birth, but significantly decreased in subsequent postnatal days. Unlike the BMI, birth weight showed significant negative (P < 0.05) correlation with the concentration of most serum metabolites, especially triglyceride, which showed negative correlation at birth and in subsequent postnatal days. We concluded that dwarfism or small body size is associated with high serum triglyceride in single-born neonatal goats, and this is probably due to the accumulation of body energy reserve in the form of body fat to compensate for lower body tissue mass.

Role of maternal variables on the development of neonatal hypoglycaemia and influence of neonatal hypoglycaemia on performance of goat kids.

The study evaluated the influence of maternal variables (age, body weight and body mass index; BMI) during mating on the development of hypoglycaemia and investigated whether hypoglycaemia at birth impairs thermoregulation, metabolism, body weight gain and immunoglobulin concentration in neonatal goat kids. Post-kidding, the kids born with hypoglycaemia (n = 19) and normoglycaemia (n = 19) were immediately identified and postnatal blood samples, body weight and cardinal physiological variables were determined. Results revealed no significant (P < 0.05) difference in pre-mating maternal variables between dams that kidded hypoglycaemic and normoglycaemic kids. Kids born with hypoglycaemia had lower (P <0.05) blood glucose concentration from birth, until Day 2, when values became comparable between the two groups. Afternoon respiratory and pulse rates were markedly (P < 0.05) unstable in kids born with hypoglycaemia and the early postnatal rise (P < 0.05) in morning rectal temperature in both groups was accompanied by a decrease (P < 0.05) on day 20 in kids born with hypoglycaemia. Blood cholesterol and triglyceride concentrations were lower (P < 0.05) in hypoglycaemic kids and the normoglycaemic kids showed marked increase (P < 0.05) in circulating immunoglobulin concentration 24 h after birth, while age had no (P > 0.05) effect in hypoglycaemic kids. A more pronounced decrease (P < 0.05) in weekly weight gain was observed in hypoglycaemic kids. It was concluded that neonatal goat kids born with hypoglycaemia may have compromised thermoregulation, metabolism and body weight gain, and the cause of hypoglycaemia in kids may not be related to pre-mating maternal variables.