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1.
Vopr Virusol ; 34(2): 217-21, 1989.
Article in Russian | MEDLINE | ID: mdl-2763514

ABSTRACT

In the experiments on dogs inoculated intracerebrally with the "paralytic rabies" variant of the "Yak" strain of street rabies virus we observed spontaneous recovery of 1 out of 5 sick animals. Rabies in this dog was verified by three isolations of the virus from the saliva during the disease and by an increase of antibody titres in the time course of to 6776. In another experiment, among 7 dogs developing rabies after intracerebral inoculation with the "convulsive rabies" variant of the virus one animal showed recurrent form of rabies. The diagnosis of rabies was confirmed by isolation of the virus from the saliva in primary disease as well as by virus isolation from the salivary glands and the brain of the dog dying with recurrent rabies.


Subject(s)
Brain Diseases/etiology , Rabies/etiology , Animals , Antibodies, Viral/analysis , Brain/microbiology , Brain Diseases/diagnosis , Brain Diseases/microbiology , Dogs , Neutralization Tests , Rabies/diagnosis , Rabies/microbiology , Rabies virus/immunology , Rabies virus/isolation & purification , Rabies virus/pathogenicity , Recurrence , Remission, Spontaneous , Saliva/microbiology , Salivary Glands/microbiology , Time Factors
2.
Vopr Virusol ; 33(2): 201-6, 1988.
Article in Russian | MEDLINE | ID: mdl-3414067

ABSTRACT

Experiments in dogs inoculated intracerebrally with biological variants of paralytic (PRV) and convulsive (CRV) rabies virus isolated from the Yak strain population of street rabies virus demonstrated distinct differences in the biological properties of the variants PRV induced in dogs paralytic rabies with a short incubation period (average 6.4 days) and CRV induced an atypical convulsive form characterized by attacks of tonic convulsions of the body, legs, and head twitching, and a longer incubation period (18.5 and 9.6 days, respectively). This explains a wide variability of the biological properties of street rabies virus strains.


Subject(s)
Genetic Variation , Rabies virus/pathogenicity , Animals , Brain/microbiology , Dogs , Mice , Rabies/microbiology , Rabies/pathology , Rabies virus/isolation & purification , Salivary Glands/microbiology , Serial Passage , Time Factors
3.
Zh Mikrobiol Epidemiol Immunobiol ; (7): 86-90, 1980 Jul.
Article in Russian | MEDLINE | ID: mdl-7435025

ABSTRACT

The tension of the rabies epidemiological situation in the regions of new constructions in Siberia and the Far East was the result of a wide spread of the infection foci and a great number of domestic animals affected by the disease. All over the territory the main-source of the infective agent for humans are dogs, and only in a few cases wild animals. In the mountainous and steppe regions of the south-eastern part of the Transbaikal territory a natural focus of rabies has been revealed. A scheme for dividing the territory into rabies epidemiological regions has been developed on the basis of studying the factors contributing to the dynamics of the epidemic and epizootic processes, as well as the epizootic situation (in the Chita and Amur regions used as an example).


Subject(s)
Disease Reservoirs/epidemiology , Rabies/epidemiology , Animals , Animals, Domestic , Animals, Wild , Dog Diseases/epidemiology , Dogs , Asia, Eastern , Foxes , Humans , Rabies/transmission , Raccoons , Rodent Diseases/epidemiology , Rodentia , Siberia
4.
Zh Mikrobiol Epidemiol Immunobiol ; (6): 128-32, 1975 Jun.
Article in Russian | MEDLINE | ID: mdl-239505

ABSTRACT

The authors present the results of bacteriological and serological study for tularemia of 498 lemmings caught in Taimyr. Positive results were revealed in 4 out of 98 sera examined in the indirect hemagglutination test. In carrying out 67 biological tests on albino mice there were isolated for the first time in the Soviet Union 6 cultures of the causative agent of tularemia from the spleen of lemmings. By morphological, cultural and virulent properties the cultures obtained failed to differ from those isolated in other regions of the Soviet Union, and, consequently, we referred to the holoarctic race. Thus, it was established by the authors (both serologically and bacteriologically) that there existed tundra foci of tularemia.


Subject(s)
Disease Reservoirs/veterinary , Rodent Diseases/microbiology , Tularemia/veterinary , Animals , Francisella tularensis/isolation & purification , Rodentia , Siberia
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