ABSTRACT
The authors compared cytotoxicity of magnetite (Fe3O4) particles in nanometric ranges (10 nm and 50 nm) and micrometer range (1 microm), analyzing changes in cellular subunits of bronchoalveolar lavage in 24 hours after intratracheal application of the particles. Findings are that the nanoparticles are more biologically aggressive than the micrometric particles, but induce more active and effective defensive reaction of alveolar fagocytosis.
Subject(s)
Bronchoalveolar Lavage Fluid/cytology , Ferrosoferric Oxide/toxicity , Metal Nanoparticles/toxicity , Phagocytosis/drug effects , Pulmonary Alveoli/metabolism , Administration, Inhalation , Animals , Bronchoalveolar Lavage Fluid/chemistry , Disease Models, Animal , Ferrosoferric Oxide/administration & dosage , Metal Nanoparticles/administration & dosage , Pulmonary Alveoli/drug effects , Pulmonary Alveoli/pathology , TracheaABSTRACT
The review covers over 230 papers published mostly in the last 5 years. The goal of the review is to attract the attention of researchers and users to stripping voltammetry in particular, its application in environmental monitoring and analysis of foodstuffs. The sensors employed are impregnated graphite, carbon paste, thick film carbon/graphite and thin film metallic electrodes modified in-situ or beforehand. Hanging mercury drop electrodes and mercury coated glassy carbon electrodes are also mentioned. Strip and long-lived sensors for portable instruments and flow through systems are discussed as devices for future development and application of stripping voltammetry.
