ABSTRACT
An investigation into albumin adhesion on ceramics was carried out, providing useful information on the relationship between the Z-potential of ceramic materials and the amount of closely adhered albumin. The chemical nature of the substance constituting the ceramic is mainly responsible for the adhesion, but additional influencing factors are also considered. A differentiation in the amount of adhesion (which is a consequence of the forces of attraction between the ceramic surface and the molecules of albumin) is found and concerns the biological quality of the materials, particularly the bioactive and bioinert ceramics.
Subject(s)
Albumins/chemistry , Biocompatible Materials/chemistry , Ceramics/chemistry , Adsorption , Chemical Phenomena , Chemistry, Physical , Electrochemistry , Hydrogen-Ion Concentration , Hydroxyapatites/chemistry , Magnesium Oxide/chemistryABSTRACT
Evaluating the properties of absorption of albumin on the surface of biomaterials is an important matter in developing information in the field of biomaterials, since it is the most abundant protein present in the human body and it is an any case the first protein that rapidly flows in quantity in a damaged area of a tissue. This study has taken into consideration three different biological glasses and the results were compared with those coming from three different biologically inert glasses. The values obtained were also compared with those coming from the measurements of the Z-potential of the same glasses to verify if a correlation between albumin absorption and Z-potential of the glasses exists. Both types of measurements were carried out at two different pH values: 4.5 and 7.4. These values were selected since the first may be indicative of an acid environment to simulate that of macrophagic action (other than of inflammatory states) and the second simulates the normal condition of a tissue like healthy bone.
