[The use of laser therapy in correcting hemostatic system disorders in patients with chronic pyelonephritis]. / Primenenie lazerterapii v korrektsii narushenii sistemy gemostaza u bol'nykh khronicheskim pielonefritom.

The paper analyzes treatment outcomes in 72 patients with chronic pyelonephritis in the phase of active inflammation. The patients have received combined therapy including laser blood radiation to correct hemostatic defects. The latter manifested as DIC syndrome resistant to antibacterial treatment. Attempts to apply transcutaneous laser radiation (TLR) and intravascular laser radiation (ILR) showed that DIC syndrome may be cured only in the combined use of the above modalities.

[The potentials of local and intravascular laser irradiation for eliminating the immunological disorders in patients with chronic pyelonephritis]. / Vozmozhnosti mestnogo i vnutrisosudistogo lazernogo oblucheniia dlia ustraneniia immunologicheskikh narushenii u bol'nykh khronicheskim pielonefritom.

61 patients suffering from chronic pyelonephritis in the stage of active inflammation associated with either urolithiasis (67.4%) or prostatic adenoma (32.6%) were divided into three groups. Group 1 received conventional antibacterial treatment, group 2 conventional treatment + local laser radiation (LLR), group 3 received combined therapy including intravascular laser irradiation of blood (IVLIB). The treatments efficacy was controlled by urine seeding for microflora and its sensitivity to antibiotics, by immunological supervision. The patients were found to have immunological abnormalities in the form of cellular and humoral immunity suppression, neutrophil phagocytic hypoactivity, elevated levels of medium-molecular peptides nonresponsive to standard antibacterial therapy. Adjuvant use of LLR improved humoral immunity and reduced total urine bacterial count. LLR replacement for IVLIB resulted in a complete regression of immunological shifts and more pronounced reduction of urinary bacterial contamination.