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J Vector Borne Dis ; 61(2): 167-175, 2024 Apr 01.
Article in English | MEDLINE | ID: mdl-38922650

ABSTRACT

BACKGROUND OBJECTIVES: The incidence of Dengue Hemorrhagic Fever (DHF) continues to increase over time in the world, including Indonesia. One of the prevention efforts against dengue virus transmission is to avoid vector mosquito bites by the use of repellants. Using repellents can reduce exposure to mosquito bites that may cause infection with the dengue virus. This study aimed to determine the effectiveness of repellent lotion composed of patchouli batik extract (Pogostemon cablin) from Southeast Sulawesi varieties against Aedes aegypti mosquitoes. METHODS: The research subjects were Aedes aegypti adult mosquitoes. The research consisted of three stages. The first stage was a phytochemical test (qualitative method), the second stage was the analysis of patchouli essential oil (GC-MS method) and the third stage was a test of the effectiveness of lotions made from patchouli extract in lotion preparations against Aedes aegypti. RESULTS: The results of the effectiveness test of patchouli leaf repellent (Pogestemon cablin) lotion preparations were as follows: for a concentration of 2.5%, protective power 81.5%; concentration 5%, protection power 83.67%; concentration 7.5%, protection power 88.64 %; the concentration of 10%, protection power 90.44%, and the concentration of 12.5% had protection power 90.89%. Probit analysis and linear regression showed the value of ProbitLc 50 was 6.631. INTERPRETATION CONCLUSION: The results of the effectiveness test of Pogestemon cablin repellent lotion preparations with the most effective concentrations were 10% and 12.5%. The results of ANOVA test indicated there was no difference in the average value of the protection power in patchouli leaves.


Subject(s)
Aedes , Insect Repellents , Plant Extracts , Pogostemon , Animals , Aedes/drug effects , Insect Repellents/pharmacology , Pogostemon/chemistry , Indonesia , Plant Extracts/pharmacology , Oils, Volatile/pharmacology , Oils, Volatile/chemistry , Female , Mosquito Vectors/drug effects , Plant Leaves/chemistry , Gas Chromatography-Mass Spectrometry
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