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Vopr Onkol ; 58(5): 644-8, 2012.
Article in Russian | MEDLINE | ID: mdl-23600281

ABSTRACT

In a prospective study the risk of subsequent gastric cancer (GC) was assessed in persons aged 45-69 over 5 years after the initial testing with a set of serological tests (pepsinogen I, pepsinogen II, gastrin-17, antibodies to Helicobacter pylori). The presence of gastric atrophy markers was a significant predictor of GC in the forthcoming years. Non-invasive techniques may be used in the formation of high-risk groups, followed by GC active surveillance.


Subject(s)
Antibodies, Bacterial/blood , Gastrins/blood , Gastritis, Atrophic/blood , Helicobacter pylori/immunology , Pepsinogens/blood , Stomach Neoplasms/blood , Aged , Biomarkers/blood , Cohort Studies , Female , Gastritis, Atrophic/enzymology , Gastritis, Atrophic/immunology , Gastritis, Atrophic/microbiology , Helicobacter Infections/blood , Helicobacter Infections/complications , Humans , Male , Middle Aged , Pepsinogen A/blood , Pepsinogen C/blood , Retrospective Studies , Serologic Tests , Stomach Neoplasms/enzymology , Stomach Neoplasms/immunology , Stomach Neoplasms/microbiology
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