1.
Emerg Infect Dis
; 18(6): 1024-6, 2012 Jun.
Article
in English
| MEDLINE
| ID: mdl-22607691
Subject(s)
Cochlear Implants , Meningitis, Pneumococcal/diagnosis , Meningitis, Pneumococcal/prevention & control , Pneumococcal Vaccines/immunology , Streptococcus pneumoniae/immunology , Antibodies, Bacterial/blood , Child, Preschool , Female , Humans , Infant , Meningitis, Pneumococcal/immunology , Meningitis, Pneumococcal/microbiology , Streptococcus pneumoniae/isolation & purification , Vaccination , Vaccines, Conjugate/immunology
2.
Vaccine
; 29(14): 2613-8, 2011 Mar 21.
Article
in English
| MEDLINE
| ID: mdl-21292008
ABSTRACT
This study reports effectiveness of trivalent influenza vaccine (TIV) against confirmed pandemic influenza infection in England using a retrospective test-negative case-control study. Cases and controls were frequency matched by age, swabbing-week and region. On univariable and multivariable analysis adjusted for underlying clinical risk factors, cases were no more or less likely than controls to be vaccinated with 2008-09 or 2007-08 season TIV. Adjusted vaccine effectiveness for the former was -6% (-43% to 22%). Vaccine effectiveness did not differ significantly by age-group or hospitalisation status. There was no evidence prior vaccination with TIV significantly altered subsequent risk of pandemic influenza H1N1 2009 infection.
