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Tunis Med ; 82(12): 1128-33, 2004 Dec.
Article in French | MEDLINE | ID: mdl-15822518

ABSTRACT

The gestationis pemphigoid is a rare auto-immune vesiculo-bulleuse dermatosis occurring during the pregnancy or of the postpartum. The diagnosis is evoked by the localization and the type of eruption like by which has occurred of successive pushes. The cutaneous biopsy in immunofluorescence confirms the diagnosis by showing the linear deposit of C3 along the basal membrane. The risk of complications fetales is high in the event of pemphigoid gestationis of or the interest of an early diagnosis and a treatment, the ci rests on the corticotherapy in topic or according to the gravity of the symptoms in general administration. From three observations and in the light of a review of the literature, the authors report the characteristics of this pathology.


Subject(s)
Pemphigoid, Bullous , Pregnancy Complications , Adrenal Cortex Hormones/administration & dosage , Adrenal Cortex Hormones/therapeutic use , Adult , Biopsy , Complement C3/analysis , Female , Fluorescent Antibody Technique, Direct , Humans , Immunoglobulin G/blood , Infant, Newborn , Male , Pemphigoid, Bullous/diagnosis , Pemphigoid, Bullous/drug therapy , Pemphigoid, Bullous/immunology , Pemphigoid, Bullous/pathology , Pregnancy , Pregnancy Complications/diagnosis , Pregnancy Complications/drug therapy , Pregnancy Complications/immunology , Pregnancy Complications/pathology , Pregnancy Outcome , Recurrence , Skin/pathology
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