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J Bacteriol ; 93(4): 1430-7, 1967 Apr.
Article in English | MEDLINE | ID: mdl-4291768

ABSTRACT

The intra-arterial infusion of hydrogen peroxide has been used as a method for producing a hyperoxic environment in experimental animals for the treatment of experimentally induced clostridial myositis. Eighty-five rabbits were employed in this study; 43 were controls and 42 were experimental animals. In the experimental study, 21 animals were treated with hydrogen peroxide by each route of administration. In this group, 52.4% of the animals receiving the intra-arterial infusion and 66.6% receiving intramuscular clysis survived. There were no survivors past 72 hr in the control group.


Subject(s)
Clostridium perfringens/drug effects , Hydrogen Peroxide/therapeutic use , Myositis/drug therapy , Animals , Female , Infusions, Parenteral , Myositis/pathology , Rabbits
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