1.
Methods Mol Biol
; 409: 341-53, 2007.
Article
in English
| MEDLINE
| ID: mdl-18450013
ABSTRACT
An iterative approach to resolving protein-peptide binding motifs is appropriate when the length of the binding protein is variable and a variety of amino acid residues may successfully occupy multiple positions. This chapter describes an iterative algorithm that first aligns binding peptides of variable lengths and then extracts a quantitative motif from the resulting alignment. Numerous examples are presented to illustrate the utility of the iterative process.