ABSTRACT
Langerhans's cell histiocytosis (LCH) is an uncommon disease characterized by an accumulation of abnormal histiocytes, together lymphocytes and eosinophils in various organs and tissues. The head and neck are frequent sites of initial presentation. We present two cases of LCH with otorhinolaryngologic symptoms. Current recommendations for diagnosis, evaluation and treatment of LCH are also discussed.
Subject(s)
Histiocytosis, Langerhans-Cell/diagnosis , Otorhinolaryngologic Surgical Procedures/methods , Child, Preschool , Diagnosis, Differential , Ear/diagnostic imaging , Ear/surgery , Eosinophilic Granuloma/diagnostic imaging , Eosinophilic Granuloma/pathology , Eosinophilic Granuloma/surgery , Female , Histiocytosis, Langerhans-Cell/drug therapy , Histiocytosis, Langerhans-Cell/surgery , Humans , Infant , Tomography, X-Ray ComputedABSTRACT
Myoepithelioma is a rare salivary gland tumor (less than 1%) which are usually located in parotid gland and minor salivary glands. Histology and immunohistochemical features of this tumors are reviewed. We report 2 cases arising in parotid and hard palate.
Subject(s)
Myoepithelioma/diagnostic imaging , Myoepithelioma/pathology , Salivary Gland Neoplasms/diagnostic imaging , Salivary Gland Neoplasms/pathology , Adult , Aged , Female , Humans , Immunohistochemistry , Keratinocytes/metabolism , Male , Myoepithelioma/metabolism , S100 Proteins/metabolism , Salivary Gland Neoplasms/metabolism , Tomography, X-Ray ComputedABSTRACT
Non-Hodgkin lymphoma (NHL) comprise 7-10% of all malignant tumors in childhood. Early systems of classification (Rappaport, Luke-Collins) have been improved with the Working Formulation. NHL are classified into low, intermediate and high-grade disease. Head and neck manifestations of Burkitt's lymphoma are encountered in less than a quarter of the reported cases and usually present as cervical adenopathy. Parapharyngeal space and extranodal disease are unusual sites of involvement. We present a case of tonsillar lymphoma diagnosed with fine-needle biopsy and confirmed with excisional biopsy. Accurate staging (stage IV) and chemotherapy regimen was promptly begun. We review the clinical aspects, pathologic features and treatment of this disease.
Subject(s)
Burkitt Lymphoma/pathology , Tonsillar Neoplasms/pathology , Antineoplastic Agents/therapeutic use , Biopsy, Needle , Burkitt Lymphoma/drug therapy , Burkitt Lymphoma/surgery , Child , Humans , Male , Tonsillar Neoplasms/drug therapy , Tonsillar Neoplasms/surgery , TonsillectomyABSTRACT
This paper studied the incidence of secretory and chronic otitis among a random group of 5,950 children, aged from 4 to 9, coming from four different climatic regions of Spain, and including a group of Gypsy children. Each of the children was given a questionnaire regarding socio-economic and environmental situation and pathological antecedents; the results for sick and normal children were then statistically analysed. The most significant aetiological factors to emerge were: low economic level, prior respiratory infection, climatic conditions, cases of rhinosinusitis and acute otitis, and family history. Among Gypsy children a much greater incidence was observed, due not to racial origin but to the greater incidence of the factors cited above.
