Subject(s)
Blood Coagulation , Platelet Aggregation , Postpartum Period/blood , Antithrombin III/analysis , Blood Coagulation Tests , Female , Fibrinolysis , Humans , Pregnancy , Time Factors , TourniquetsSubject(s)
Epoprostenol/blood , Platelet Aggregation , Postpartum Period/blood , Thromboxane B2/blood , Female , Humans , Pregnancy , Time Factors , TourniquetsABSTRACT
PIP: Based on reference data, the opinions concerning the effect of copper ions on reproductive processes were presented. Special attention was paid to the effect of IUDs provided with copper ions upon the mechanism of uterine contractility. (author's)^ieng
Subject(s)
Contraception , Copper/physiology , Intrauterine Devices, Copper , Endometrium/drug effects , Endometrium/physiology , Female , Humans , Prostaglandins F/biosynthesis , Stimulation, ChemicalABSTRACT
It has been found that R-805 reduces and then eliminates the contractile activity of the isolated rat myometrium. R-805 weakens and then abolishes the reaction of the myometrium to polypeptides (oxytocin, vasopressin, bradykinin and hypertensin). In the presence of R-805, exogenous prostaglandin F(2) alpha restores the myometrial reactivity to the investigated polypeptides. On the basis of the obtained results and data from the literature a tentative hypothesis has been put forward as to the mechanism of R-805 action on the myometrial reactivity to polypeptides.
