Oral pemphigus treated with minipulse therapy

Pemphigus is a chronic potentially fatal autoimmune disorder that causes blisters and erosions of the skin and oral mucous membrane. most of the cases present oral manifestations as the first clinical sign along with dermal lesions. only 0.5 to 3.2 of cases are reported each year per 1,000,000 population with oral manifestations without dermal participation, and is at times difficult to diagnose. we report a case of oral pemphigus vulgaris in a 20 year old female patient without dermal manifestations treated with oral mini pulse therapy. pénfigo oral tratado con terapia minipulse. resumen: el pénfigo es un trastorno autoinmune crónico potencialmente fatal que causa ampollas y erosiones de la piel y la membrana mucosa oral. la mayoría de los casos presentan manifestaciones orales como el primer signo clínico junto con lesiones dérmicas. solo se reportan de 0.5 a 3.2 casos cada año por cada 1,000,000 de personas con manifestaciones orales sin afectación de la piel, y algunas veces es difícil de diagnosticar. presentamos un caso de pénfigo vulgar oral en un paciente de 20 años, sin manifestaciones cutáneas tratadas con mini terapia del pulso oral.

Extrafollicular Adenomatoid Odontogenic Tumor: An Unusual Case Presentation.

Adenomatoid odontogenic tumor (AOT) is an uncommon tumor of odontogenic origin and often misdiagnosed as an odontogenic cyst. It is predominantly found in young female patients, located more often in maxilla, and in most cases associated with an unerupted permanent tooth. There are three variants of AOT namely follicular, extra follicular, and peripheral. We report an unusual case of extrafollicular AOT in maxilla of a 50-year old male patient.

Mucocutaneous manifestations of Cowden's syndrome.

Cowden's syndrome is an autosomal dominant genodermatosis with variable orofacial and systemic manifestations. Here we present one such classical case of Cowden's syndrome in a 45-year-old female patient with features such as multiple cutaneous papillomatosis, oral fibromas, and fibromas involving multiple organs such as gastrointestinal tract (multiple polyps), thyroid disorders, and breast cancer.

Ambras Syndrome with Gingival Hyperplasia: A Rare Entity.

Ambras syndrome is a rare and special form of congenital hypertrichosis, characterized by dysmorphic facial features and familial pattern of inheritance. It is rarely associated with gingival hyperplasia. We report such a rare entity in a 38-year-old female patient with a history of consanguinity and positive family history.

Photodynamic Therapy - A Non-invasive Treatment Modality for Precancerous Lesions.

INTRODUCTION: Oral premalignant lesions are conditions having high potential tendency for transformation into malignancy. The use of a conservative and effective treatment modality is one of the best strategies for cancer prevention. Photodynamic therapy (PDT) is a non-invasive method for topical and selective treatment of oral precancerous lesions. The present study was taken up to determine the efficacy of PDT in oral precancerous lesions. METHODS: The study consisted 13 patients with 24 oral leukoplakia (OL) lesions and 8 with 20 oral lichen planus (OLP) lesions, divided into control and study groups. These lesions were affecting various intraoral sites, the buccal mucosa being the most common site followed by tongue and gingiva. The treatment regimen of PDT included 98% 5-aminolevulinic acid (5-ALA) which is topical applied and irradiated with light emitting diode (LED) of 420 nm wavelengths at several sessions. RESULTS: In OL 16.6% of cases showed complete response, 66.6% partial response and 16.6% no response of the lesions to the treatment. In OLP 80% and 20% of the lesions showed partial and no response respectively. The differences with control groups for OL + OLP were found to be significant (P < 0.001). CONCLUSION: Based on the results of the present study, we can conclude that PDT appears to be a feasible alternative to conventional therapy for oral premalignant lesions.

Efficacy of Diode Laser for the Management of Potentially Malignant Disorders.

INTRODUCTION: Laser dentistry is a one of the upcoming advanced treatment modality for oral mucosal lesions. Diode laser is a soft tissue laser that has found much acceptance in all branches of dentistry. Available compact size and feasibility has render diode laser an enhanced tool for today's clinical practice. The aim of this study is to determine the efficacy and safety of diode laser for the management of white lesions such as oral leukoplakia (OL) and oral lichen planus (OLP). METHODS: The study was conducted by using diode laser 980 nm on 10 patients with white lesions (5 OL and 5 OLP) aged between 35 to 65 years. RESULTS: Of the 10 patients (5 OL and 5 OLP), 3 patients (30%) complained of moderate pain and 7 patients (70%) complained of mild pain, for first 3 days after laser irradiation, and pain disappeared at end of first week. There was no recurrence of the lesion during the 6-month follow up. CONCLUSION: Diode lasers provide acceptable clinical improvement of potentially malignant lesions with minimal side effects. It can be considered one of the best alternative treatment modality for oral mucosal lesions.

Lipoma or hemangioma: A diagnostic dilemma?

Lipomas and hemangiomas are well-known benign lesions of the body. However, their occurrence in the oral cavity is rare. Lipoma accounts for 1-4% of benign neoplasms of mouth affecting predominantly the buccal mucosa, floor of mouth and tongue. Hemangiomas occur mostly on the lips, buccal mucosa, tongue, and palate. Lipomas when superficially placed show yellowish surface discoloration and hemangiomas usually have reddish blue to deep blue color. Here, we report an unusual case of benign tumor occurring in the buccal vestibule.

Craniofacial fibrous dysplasia--a Morbid presentation.

Fibrous dysplasia is grouped under fibro-osseous lesions with developmental anomaly of bone forming mesenchyme that manifests as a defect in osteoblastic differentiation and maturation. This paper describes a case of 28 yrs old female who presented with swelling on right side of face, nostril and intraoral swelling on right half of hard palate since 1-year. The diagnosis was based on clinico-radiological and histopathological investigations. The appropriate management of patient included surgical modality along with placement of obturator to fill the defect. Follow up was done and till date there is no recurrence.

Bullous Lichen Planus treated with Oral Minipulse Therapy: A Rare Case Report.

Oral Lichen planus (OLP) is a common mucocutaneous disorder with a multifactorial aetiology, affecting the women more commonly than men. Most OLP are asymptomatic, except the atrophic and erosive forms.Till date many treatment modalities are implicated to treat this disorder, but no therapy is considered as the single most effective, without side-effects and remission of the lesion. As the treatment of OLP is challenging to the oral practitioners, here we report a case of successful management of extensive, symptomatic bullous and erosive oral lichen planus with a novel treatment protocol- oral minipulse therapy with betamethasone.

Cheiloscopy, Palatoscopy and Odontometrics in Sex Prediction and Dis-crimination - a Comparative Study.

BACKGROUND AND OBJECTIVES: Human identification is the forensic odontologist's primary duty in the fields like violent crime, child abuse, elder abuse, missing persons and mass disaster scenarios. In each context, dental traits may produce compelling evidence to aid victim identity, suspect identity and narrow down the outcome of investigative casework. Sometimes it becomes necessary to apply some least known and less popular techniques in identification procedure where lip prints, rugae patterns and canine odontometrics can give us comparatively valid conclusions pertaining to person's identification. This study elucidates the significance of cheiloscopy, palatoscopy and canine odontometry in sex prediction and discrimination. MATERIALS AND METHODS: A cross- sectional study involving a total of 60 subjects, 30 males and 30 females were selected from the outpatient department of oral medicine and radiology. Lip prints were recorded using lipstick, palatal impressions were taken with alginate and odontometric measurements were taken with digital vernier calipers from every subject. All the obtained records were analyzed by two observers. RESULTS: Reliability of lip prints was assessed using Kappa coefficient. Comparison of rugae patterns was done using Chi-square test. Mean canine and inter canine width was compared using t test. A p-value of <0.05 was considered significant. Statistically significant difference was found with the different lip print patterns analyzed in males and females, while no significant difference was observed in the rugae patterns but a significant difference in the mesio-distal width of mandibular canines in males and females was found with right mandibular canine(3.73%) showing greater sexual dimorphism compared to left mandibular canine(3.06%). CONCLUSION: This study shows the uniqueness of the lip prints and rugae patterns with the lip prints showing sensitivity of 81.7% giving reliable prediction of sex over palatoscopy. Hence, cheiloscopy along with the canine odontometrics aid in sex determination and can be considered as an ancilliary forensic tool in identification.

Unicystic mural ameloblastoma: an unusual case report.

Ameloblastoma is a benign odontogenic neoplasm which frequently affects the mandible. The term ameloblastoma includes several clinicoradiological and histological types. Apart from the most commonly encountered clinicopathologic models, there are few variants, whose biological profile is unknown or not elicited. Among these types, unicystic ameloblastoma is the least encountered variant of the ameloblastoma. Unicystic ameloblastoma refers to those cystic lesions that show clinical, radiographic, or gross features of a jaw cyst but on histologic examination show a typical ameloblastomatous epithelium lining the cyst cavity, with or without luminal and/or mural tumor proliferation. Unicystic ameloblastoma is a less encountered variant of the ameloblastoma and is believed to be less aggressive. As this tumor shows considerable similarities with dentigerous cysts, both clinically and radiographically, the biologic behaviour of this tumor group was reviewed. Moreover, recurrence of unicystic ameloblastoma may be long delayed, and a long-term postoperative followup is essential for proper management of these patients. Here we are presenting a case of unicystic ameloblastoma in an 18-year-old female patient.