1.
Bull Exp Biol Med
; 159(2): 248-52, 2015 Jun.
Article
in English
| MEDLINE
| ID: mdl-26085359
ABSTRACT
Immunohistochemical assay with double label and confocal laser scanning microscopy showed that innate immunity receptor TLR4 is expressed predominantly in neurons of the intestinal Auerbach (myenteric) plexus, while vanilloid nociceptive receptor TRPV1 is expressed by neurons of Meissner (submucous) plexus. Immunohistochemical analysis with triple labeling revealed coexpression of TLR4 and TRPV1 in enteric neurons of rat colon. The results attest to a possibility of functional interaction between Toll-like and vanilloid receptors in the neuron level.
Subject(s)
Colon/innervation , Myenteric Plexus/metabolism , Nociceptors/metabolism , Receptors, Pattern Recognition/metabolism , Submucous Plexus/metabolism , TRPV Cation Channels/metabolism , Toll-Like Receptor 4/metabolism , Animals , Colon/metabolism , Immunohistochemistry , Male , Microscopy, Confocal , Rats , Rats, Sprague-Dawley , Statistics, Nonparametric
2.
Dokl Biol Sci
; 452: 269-72, 2013 Sep.
Article
in English
| MEDLINE
| ID: mdl-24150644
Subject(s)
Myenteric Plexus/metabolism , Submucous Plexus/metabolism , TRPV Cation Channels/metabolism , Toll-Like Receptor 4/metabolism , Animals , Intestinal Mucosa/metabolism , Intestines/innervation , Male , Myenteric Plexus/cytology , Neurons/metabolism , Organ Specificity , Rats , Rats, Sprague-Dawley , Submucous Plexus/cytology , TRPV Cation Channels/genetics , Toll-Like Receptor 4/genetics
3.
Dokl Biol Sci
; 445: 215-7, 2012.
Article
in English
| MEDLINE
| ID: mdl-22945519
4.
Vestn Dermatol Venerol
; 46(8): 21-4, 1972 Aug.
Article
in Russian
| MEDLINE
| ID: mdl-5056795
