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Int J Environ Res Public Health ; 5(2): 120-4, 2008 Jun.
Article in English | MEDLINE | ID: mdl-18678927

ABSTRACT

Use of Juvenile Hormone Analogues (JHA) in sericulture practices has been shown to boost good cocoon yield; their effect has been determined to be dose-dependent. We studied the impact of low doses of JHA compounds such as methoprene and fenoxycarb on selected key enzymatic activities of the silkworm Bombyx mori. Methoprene and fenoxycarb at doses of 1.0 microg and 3.0 fg/larvae/48 hours showed enhancement of the 5th instar B. mori larval muscle and silkgland protease, aspartate aminotransaminase (AAT) and alanine aminotransaminase (ALAT), adenosine triphosphate synthase (ATPase) and cytochrome-c-oxidase (CCO) activity levels, indicating an upsurge in the overall oxidative metabolism of the B.mori larval tissues.


Subject(s)
Bombyx/drug effects , Bombyx/enzymology , Methoprene/pharmacology , Phenylcarbamates/pharmacology , Adenosine Triphosphatases/drug effects , Alanine Transaminase/drug effects , Animals , Aspartate Aminotransferases/drug effects , Bombyx/physiology , Dose-Response Relationship, Drug , Electron Transport Complex IV/drug effects , Energy Metabolism/drug effects , Energy Metabolism/physiology , Gene Expression Regulation, Developmental , Juvenile Hormones/metabolism , Larva/drug effects , Larva/growth & development , Metamorphosis, Biological/drug effects , Metamorphosis, Biological/physiology
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