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[Study of the repair enzyme O6-alkylguanine-DNA-alkyltransferase presence in mammalian cells in vitro]. / Vyznachennia naiavnosti reparatyvnoho fermentu O6-alkihuanin-DNK-alkiltransferazy v klitynakh ssavtsiv in vitro.
Lylo, V V; Man'ko, V H; Nemazanyi, I O; Kovalenko, O O; Matsevych, L L; Lukash, L L.
Tsitol Genet ; 38(6): 67-70, 2004.
Article in Ukrainian | MEDLINE | ID: mdl-15882038

ABSTRACT

The enzyme O6-alkylguanine-DNA-alkyltransferase (AGT) has been revealed to be present in human cell cultures (fibroblasts and cardiomyocytes) and Chinese hamster culture cells. At the same time the enzyme AGT is not reproduced in the human brain shell culture cells.


Subject(s)
Fibroblasts/enzymology , Myocytes, Cardiac/enzymology , O(6)-Methylguanine-DNA Methyltransferase/analysis , Animals , CHO Cells , Cells, Cultured , Cricetinae , Cricetulus , DNA Repair , Humans , O(6)-Methylguanine-DNA Methyltransferase/genetics , O(6)-Methylguanine-DNA Methyltransferase/metabolism
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