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Pediatrics ; 109(2): 325-7, 2002 Feb.
Article in English | MEDLINE | ID: mdl-11826216

ABSTRACT

A 2-year-old girl presented with vomiting and diarrhea 7 hours after eating a large quantity of ginkgo seeds. She exhibited an afebrile convulsion 9 hours after ingestion. The serum concentration of 4-metoxypyridoxine was as high as 360 ng/mL. Although reported cases of ginkgo seed poisoning usually involve children who exhibit repetitive seizures that can be fatal, prompt administration of pyridoxal phosphate (2 mg/kg) may have prevented additional seizures. This is the first English-language case report measuring 4-metoxypyridoxine concentration during ginkgo seed poisoning. Awareness of the potential danger of overconsumption of this traditional food and its prompt treatment with pyridoxal phosphate may hasten recovery.


Subject(s)
Foodborne Diseases/drug therapy , Ginkgo biloba/poisoning , Pyridoxal Phosphate/therapeutic use , Pyridoxine/analogs & derivatives , Child, Preschool , Female , Ginkgo biloba/chemistry , Humans , Pyridoxine/poisoning , Seeds/chemistry , Seeds/poisoning , Treatment Outcome
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