ABSTRACT
BACKGROUND: Parathyroid metastatic disease from thyroid cancer has not been studied extensively, mainly due to the need for parathyroid preservation during thyroid surgery. METHODS: We reviewed files from 1,770 patients with thyroid cancer followed up in our department and 10 patients with parathyroid metastases (0.5%) were identified. Patient and tumor characteristics were recorded. RESULTS: Six out of ten patients had metastases from papillary thyroid cancer, three from follicular thyroid cancer and one from anaplastic thyroid cancer. In nine patients parathyroid infiltration from thyroid cancer was found in direct contact with the thyroid cancer, and in one patient metastatic foci were observed not in continuity with the thyroid cancer. CONCLUSIONS: Parathyroid involvement, although infrequent, may occur in thyroid cancer independently of patient age and tumor size. The clinical significance of such event is not clear. The influence on disease outcome remains to be elucidated.
Subject(s)
Adenocarcinoma, Follicular/pathology , Carcinoma, Papillary/pathology , Carcinoma/pathology , Parathyroid Neoplasms/secondary , Thyroid Neoplasms/pathology , Adolescent , Adult , Aged , Cohort Studies , Female , Humans , Male , Middle Aged , Neoplasm Staging , PrognosisABSTRACT
Neuromuscular and vascular hamartoma (NMVH) is a very rare stricturing condition of the small intestine, occurring focally and causing recurrent obstructive symptoms or occult chronic gastrointestinal bleeding. Salas et al. (Neuromesenchymal hamartoma of the small bowel. J Clin Gastroenterol. 1990, 12 (6): 705-9) proposed the term of "Neuromesenchymal hamartoma" for the cases of NMVH with participation of mesenchymal tissues.We present the case of a 60-year-old male patient admitted twice in a month with abdominal pain. On the third admission with clinical signs of acute abdomen, an exploratory laparotomy was performed. The clinical and laboratory findings that occurred after the patient's evaluation, the intraoperative findings and the pathological features of this lesion are reported.
Subject(s)
Hamartoma/pathology , Intestinal Neoplasms/pathology , Intestine, Small/pathology , Mesoderm/pathology , Nerve Fibers/pathology , Hamartoma/complications , Hamartoma/surgery , Humans , Intestinal Neoplasms/complications , Intestinal Neoplasms/surgery , Intestinal Obstruction , Intestine, Small/surgery , Laparotomy , Male , Mesentery , Mesoderm/surgery , Middle AgedABSTRACT
Osteomyelitis as a medical term defining a specific type of infection may be classified in acute and chronic form. In our case an acute mandibular osteomyelitis is reported with evaluation of the clinical and histological examination. The biological course of the disease determined on that basis. The significance of this report focused on the early diagnosis and the possible need for bone biopsy.
