1.
J Nat Prod
; 64(6): 842-4, 2001 Jun.
Article
in English
| MEDLINE
| ID: mdl-11421762
ABSTRACT
Two new steroidal alkaloids, (-)-vaganine D (1) [(20S)-20-(N,N-dimethylamino)-3 beta-(senecioylamino)-5 alpha-pregn-16-en-4 beta-yl acetate], and (+)-nepapakistamine A (2) [(20S)-20-(N-methylamino)-3 beta-(tigloylamino)-5 alpha-pregn-16-en-2 beta,4 beta-diacetate], were isolated from the leaves of Sarcococca coriacea. Their structures were elucidated on the basis of their spectral properties. Compounds 1 and 2 were found to be cholinesterase inhibitors.
Subject(s)
Cholinesterase Inhibitors/chemistry , Cholinesterase Inhibitors/pharmacology , Plants, Medicinal/chemistry , Progesterone/chemistry , Progesterone/pharmacology , Animals , Cholinesterase Inhibitors/isolation & purification , Electrophorus , Horses , Magnetic Resonance Spectroscopy , Mass Spectrometry , Nepal , Plant Leaves/chemistry , Progesterone/analogs & derivatives , Spectrophotometry, Infrared , Spectrophotometry, Ultraviolet
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4.
Experientia
; 33(2): 153, 1977 Feb 15.
Article
in English
| MEDLINE
| ID: mdl-844530
