1.
Ukr Biokhim Zh (1978)
; 57(1): 79-82, 1985.
Article
in Russian
| MEDLINE
| ID: mdl-3976019
ABSTRACT
The level of certain parameters of lipid peroxidation and the activity of lysosome hydrolases were studied on the shock model in rats. It was established that the traumatic shock in the experiment is accompanied by the growth of the level of over-oxidation products (malonic dialdehyde, diene conjugates), the rate of erythrocyte hemolysis as well as by an increase in the hydrolase activity. Administration of ionol (60 mg/kg) inhibits the higher activity of radical-free lipid oxidation, decreases the damage of membrane structure and the metabolism disturbance.
Subject(s)
Butylated Hydroxytoluene/therapeutic use , Lipid Peroxides/metabolism , Shock, Traumatic/metabolism , Animals , Enzyme Activation/drug effects , Female , Hydrolases/blood , Hydrolases/metabolism , Kidney/metabolism , Lipid Peroxides/blood , Liver/metabolism , Lysosomes/enzymology , Male , Rats , Shock, Traumatic/drug therapy
2.
Patol Fiziol Eksp Ter
; (6): 83-6, 1984.
Article
in Russian
| MEDLINE
| ID: mdl-6097862
Subject(s)
Hypothalamo-Hypophyseal System/physiopathology , Pituitary-Adrenal System/physiopathology , Shock/physiopathology , 11-Hydroxycorticosteroids/metabolism , Adrenocorticotropic Hormone/metabolism , Corticotropin-Releasing Hormone/antagonists & inhibitors , Corticotropin-Releasing Hormone/metabolism , Corticotropin-Releasing Hormone/physiology , Humans , Shock/prevention & control
3.
Patol Fiziol Eksp Ter
; 13(1): 79-80, 1969.
Article
in Russian
| MEDLINE
| ID: mdl-5376895