Reversible Cerebral Atrophy in Infantile Tremor Syndrome.

BACKGROUND: We report changes in MRI brain of children with Infantile Tremor Syndrome (ITS) at the onset of illness and following treatment. CASE CHARACTERISTICS: Three children with infantile tremor syndrome were assessed for changes in brain neuroimaging at admission and at follow-up visit. On MRI, all children had mild to severe diffuse cerebral atrophy, which reverted back to normal on follow-up visits. OUTCOME: Children with infantile tremor syndrome have reversible diffuse cerebral atrophy on neuroimaging.