1.
Med J Aust
; 204(7): 277-8, 2016 Apr 18.
Article
in English
| MEDLINE
| ID: mdl-27078606
Subject(s)
Bacterial Proteins/biosynthesis , Drug Resistance, Bacterial , Klebsiella pneumoniae/enzymology , beta-Lactamases/biosynthesis , Azabicyclo Compounds/therapeutic use , Carbapenems/pharmacology , Ceftazidime , Humans , Klebsiella Infections/drug therapy , Klebsiella pneumoniae/drug effects , Male , Metronidazole/therapeutic use , Middle Aged , Pancreatic Diseases/microbiology , Teicoplanin/therapeutic use
2.
Aust N Z J Obstet Gynaecol
; 51(4): 372-6, 2011 Aug.
Article
in English
| MEDLINE
| ID: mdl-21806575
ABSTRACT
Trastuzumab increases survival amongst women with human epidermal growth factor receptor (HER)-2 receptor positive metastatic breast cancer, but maternal and fetal risks are associated with advanced disease and its treatment in pregnancy. We present a case of a primigravid with HER-2 positive metastatic breast cancer who received trastuzumab throughout pregnancy. She presented with cerebral metastases, requiring surgical decompression and resection. Reversible oligohydramnios developed during pregnancy. Fetal safety data on trastuzumab in pregnancy is limited, but case reports suggest a recurring pattern of (mostly reversible) oligohydramnios.