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1.
Saudi J Biol Sci ; 22(5): 580-4, 2015 Sep.
Article in English | MEDLINE | ID: mdl-26288562

ABSTRACT

Silages from pineapple peel, sweet corn husk and cob mixed with bagasse and vinasse were evaluated to determine their chemical composition and fermentation characteristics as well as feeding performance in fattening steers. The experiment, which lasted 90 days, involved 48 fattening steers (264 ± 37.4 kg BW) randomly allocated to three diets. Treatments included: a control diet containing rice straw and molasses (T1); diet containing bagasse-vinasse mixture including sweet corn husk and cob silage (BS; T2); and diet containing bagasse-vinasse mixture including pineapple peel silage (BP; T3). All treatments included a commercial concentrate feed (13% CP) and ad libitum rice straw throughout the experiment. Results from chemical analysis showed that dry matter (DM) of BS was higher than BP (P < 0.05), whereas the protein content of BS and BP was similar (P > 0.05). For fermentation characteristics, pH in BP was lower than BS (P < 0.05); in addition, acetic and butyric acids in BS were higher than BP (P < 0.05). Findings from growth trial showed that total DM intake in steers fed T1 was higher compared to the other dietary treatments (P < 0.05), whereas the average BW gain was found to be grater in T3 steers (P < 0.05). As result from our findings, bagasse-vinasse mixture with pineapple peel silage appeared to be a viable feed ingredient in fattening steer diet and moreover it could become an economically feasible agro-industrial by-product for farmers.

2.
Phytomedicine ; 15(12): 1130-4, 2008 Dec.
Article in English | MEDLINE | ID: mdl-18617378

ABSTRACT

Five limonoids isolated from the seeds of Chisocheton siamensis were tested for their antimalarial activity against Plasmodium falciparum, antimycobacterial activity against Mycobacterium tuberculosis and cytotoxic activity against NCI-H187 (human small cell lung cancer), KB (oral human epidermal carcinoma) and MCF-7 (breast cancer) cancer cell lines. All limonoids (1-5) showed inhibitory effect against Plasmodium falciparum with IC(50) values ranging from 2.06 to 6.31 microg/ml. Only azadiradione (2) exhibited strong inhibitory effect against Mycobacterium tuberculosis with the MIC of 6.25 microg/ml. Compounds 1-4 also showed cytotoxic activity against NCI-H187, KB and MCF-7 cancer cell lines and dysobinine (1) had the highest activity with IC(50) of 1.67, 3.17 and 2.15 microg/ml, respectively.


Subject(s)
Anti-Bacterial Agents/pharmacology , Antimalarials/pharmacology , Antineoplastic Agents/pharmacology , Limonins/pharmacology , Meliaceae/chemistry , Animals , Anti-Bacterial Agents/isolation & purification , Antimalarials/isolation & purification , Antineoplastic Agents/isolation & purification , Cell Line, Tumor , Humans , Limonins/isolation & purification , Mycobacterium tuberculosis/drug effects , Plant Extracts/chemistry , Plasmodium falciparum/drug effects , Seeds/chemistry
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