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1.
JACC Clin Electrophysiol ; 7(11): 1358-1365, 2021 11.
Article in English | MEDLINE | ID: mdl-34217658

ABSTRACT

OBJECTIVES: This study set out to examine outcomes from pediatric supraventricular tachycardia ablations over a 20-year period. This study sought to examine success rates and repeat ablations over time and to evaluate whether modalities such as 3-dimensional (3D) mapping, contact force, and cryotherapy have improved outcomes. BACKGROUND: Ablation of supraventricular tachycardia in pediatric patients is commonly performed in most congenital heart centers with excellent long-term results. METHODS: Data were retrieved from the NICOR (National Institute of Clinical Outcomes Research) database in the United Kingdom. Outcomes over time were evaluated, and procedure-related details were compared. RESULTS: There were 7,069 ablations performed from January 1, 1999, to December 31, 2018, at 10 centers. Overall, ablation success rates were 92% for accessory pathways, 97% for atrioventricular node re-entry tachycardia, and 89% for atrial tachycardia. There was an improvement in procedural success rates over time (p < 0.01). The use of 3D mapping did not alter success or need for repeat ablation but was associated with a higher proportion of lower fluoroscopy cases; 55% of 3D mapping cases used <5 min of fluoroscopy (p < 0.01). Patients needing a repeat ablation were 341 (12%) for accessory pathways, 128 (7%) for atrioventricular node re-entry tachycardia, and 35 (7%) for atrial tachycardia. Overall, the risk of complete heart block was low (n = 12, <0.01%). The use of cryotherapy was associated with an increased risk of needing a repeat ablation. CONCLUSIONS: Overall success rates from pediatric ablations are excellent and compare favorably to other registries. Introduction of newer technologies have likely made procedures safer and reduced radiation exposure, but they have not changed success rates or the need for a repeat procedure.


Subject(s)
Accessory Atrioventricular Bundle , Catheter Ablation , Tachycardia, Atrioventricular Nodal Reentry , Tachycardia, Supraventricular , Child , Fluoroscopy , Humans , Tachycardia, Atrioventricular Nodal Reentry/surgery , Tachycardia, Supraventricular/epidemiology , Tachycardia, Supraventricular/surgery
2.
Eur J Pediatr ; 167(2): 233-5, 2008 Feb.
Article in English | MEDLINE | ID: mdl-17486364

ABSTRACT

We describe a teenage girl who presented with syncope on exertion and prolonged QT on electrocardiogram (ECG). She was found to be hypocalcaemic due to hypoparathyroidism. Following oral calcium and vitamin D supplementation, there were no further episodes of syncope with normalization of the QT segment. This case highlights the need to consider all causes of a long QT segment.


Subject(s)
Hypocalcemia/diagnosis , Hypoparathyroidism/diagnosis , Long QT Syndrome/diagnosis , Syncope/etiology , Adolescent , Diagnosis, Differential , Electrocardiography , Female , Humans , Hypocalcemia/complications , Hypoparathyroidism/complications
3.
J Heart Lung Transplant ; 26(6): 658-60, 2007 Jun.
Article in English | MEDLINE | ID: mdl-17543795

ABSTRACT

We report a favorable outcome in a child who underwent cardiac transplantation for severe early post-anthracycline-induced cardiomyopathy, 9 months after completion of treatment for acute myeloid leukemia (AML). The child suffered a relapse of AML 2 months after cardiac transplantation and then underwent a successful bone marrow transplant. This case is unique in the literature. We believe it offers an alternative strategy for children with hematologic malignancies, where severe early post-anthracycline cardiotoxicity might preclude bone marrow transplantation.


Subject(s)
Anthracyclines/toxicity , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Bone Marrow Transplantation , Heart Transplantation , Leukemia, Myeloid, Acute/drug therapy , Child , Humans , Male , Pancytopenia/etiology , Recurrence , Survivors
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