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Cancer ; 70(2): 554-6, 1992 Jul 15.
Article in English | MEDLINE | ID: mdl-1617605

ABSTRACT

The authors report the case of a patient with a Hickman catheter that migrated into the lung parenchyma. The resultant inadvertent infusion of 5-fluorouracil caused necrotizing chemical pneumonitis. Possible mechanisms of catheter migration include the lateral orientation of the catheter tip and the partial thrombosis of the innominate vein and superior vena cava. The patient recovered but had residual contraction fibrosis of the right upper lobe of the lung.


Subject(s)
Catheters, Indwelling/adverse effects , Fluorouracil/administration & dosage , Foreign-Body Migration/complications , Infusions, Intravenous/adverse effects , Lung/pathology , Pneumonia/chemically induced , Aged , Brachiocephalic Veins , Fluorouracil/adverse effects , Humans , Lung/drug effects , Male , Necrosis , Pneumonia/pathology , Superior Vena Cava Syndrome/etiology , Thrombosis/etiology
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